• 1
    Appleby, J.L., Parkinson, S., Bourret, R.B. (1996) Signal transduction via the multi-step phosphorelay: not necessarily a road less traveled. Cell 86: 845848.
  • 2
    Arico, B., Miller, J.F., Roy, C., Stibitz, S., Monack, D., Falkow, S., et al (1989) Sequences required for expression of Bordetella pertussis virulence factors share homology with prokaryotic signal transduction proteins. Proc Natl Acad Sci USA 86: 66716675.
  • 3
    Bassler, B.L. (1999a) A multichannel two-component signaling relay controls quorum sensing in Vibrio harveyi. In Cell-Cell Signaling in Bacteria. Dunny, G.M., and Winans, S.C. (eds). Washington, DC: American Society for Microbiology Press, pp. 259273.
  • 4
    Bassler, B.L. (1999b) How bacteria talk to each other: regulation of gene expression by quorum sensing. Curr Opin Microbiol (in press).
  • 5
    Bassler, B.L., Wright, M., Showalter, R.E., Silverman, M.R. (1993) Intercellular signalling in Vibrio harveyi: sequence and function of genes regulating expression of luminescence. Mol Microbiol 9: 773786.
  • 6
    Bassler, B.L., Wright, M., Silverman, M.R. (1994a) Multiple signalling systems controlling expression of luminescence in Vibrio harveyi: sequence and function of genes encoding a second sensory pathway. Mol Microbiol 13: 273286.
  • 7
    Bassler, B.L., Wright, M., Silverman, M.R. (1994b) Sequence and function of luxO, a negative regulator of luminescence in Vibrio harveyi. Mol Microbiol 12: 403412.
  • 8
    Bassler, B.L., Greenberg, E.P., Stevens, A.M. (1997) Cross-species induction of luminescence in the quorum-sensing bacterium Vibrio harveyi. J Bacteriol 179: 40434045.
  • 9
    Beringer, J.E., Beynon, J.L., Buchanan-Wollaston, A.V., Johnston, A.W.B. (1978) Transfer of the drug resistance transposon Tn5 to Rhizobium. Nature 276: 633634.
  • 10
    Brissette, R.E., Tsung, K., Inouye, M. (1991) Suppression of a mutation in OmpR at the putative phosphorylation center by a mutant EnvZ protein in Escherichia coli. J Bacteriol 173: 601608.
  • 11
    Burbulys, D.K., Trach, K.A., Hoch, J.A. (1991) The initiation of sporulation in Bacillus subtilis is controlled by a multicomponent phosphorelay. Cell 64: 545552.
  • 12
    Cao, J. & Meighen, E.A. (1989) Purification and structural identification of an autoinducer for the luminescence system of Vibrio harveyi. J Biol Chem 264: 2167021676.
  • 13
    Ditta, G., Stanfield, S., Corbin, D., Helinski, D. (1980) Broad host range DNA cloning system for gram-negative bacteria: construction of a gene bank of Rhizobium meliloti. Proc Natl Acad Sci USA 77: 73477351.
  • 14
    Fellay, R., Frey, J., Krisch, H. (1987) Interposon mutagenesis of soil and water bacteria: a family of DNA fragments designed for in vitro insertional mutagenesis of Gram-negative bacteria. Gene 52: 147154.
  • 15
    Freeman, J.A. & Bassler, B.L. (1999a) Sequence and function of LuxU: a two-component phosphorelay protein that regulates quorum sensing in Vibrio harveyi. J Bacteriol 181: 899906.
  • 16
    Freeman, J.A. & Bassler, B.L. (1999b) A genetic analysis of the function of LuxO, a two-component response regulator involved in quorum sensing in Vibrio harveyi. Mol Microbiol 31: 665677.
  • 17
    Friedman, A., Long, S.R., Brown, S.E., Buikema, W.J., Ausubel, F. (1982) Construction of a broad host range cosmid cloning vector and its use in the genetic analysis of Rhizobium mutants. Gene 18: 289296.
  • 18
    Georgellis, D., Lynch, A.S., Lin, E.C.C. (1997) In vitro phosphorylation study of the Arc two-component signal transduction system of Escherichia coli. J Bacteriol 179: 54295435.
  • 19
    Georgellis, D., Kwon, O., De Wulf, P., Lin, E.C.C. (1998) Signal decay through a reverse phosphorelay in the Arc two-component signal transduction system. J Biol Chem 273: 3286432869.
  • 20
    Greenberg, E.P., Hastings, J.W., Ulitzer, S. (1979) Induction of luciferase synthesis in Beneckea harveyi by other marine bacteria. Arch Microbiol 120: 8791.
  • 21
    Hsing, W. & Silhavy, T.J. (1997) Function of conserved histidine-243 in phosphatase activity of EnvZ, the sensor for porin osmoregulation in Escherichia coli. J Bacteriol 179: 37293735.
  • 22
    Iuchi, S., Matsuda, T., Fujiwara, T., Lin, E.C.C. (1990) The arcB gene of Escherichia coli encodes a sensor-regulator protein for anaerobic repression of the arc modulon. Mol Microbiol 4: 715727.
  • 23
    Manoil, C.M. & Beckwith, J. (1985) TnphoA: a transposon probe for protein export signals. Proc Natl Acad Sci USA 82: 81298133.
  • 24
    Michael, S.F. (1994) Mutagenesis by incorporation of a phosphorylated oligo during PCR amplification. Biotechniques 16: 410412.
  • 25
    Parkinson, J. & Kofoid, E.C. (1992) Communication modules in bacterial signaling proteins. Annu Rev Genet 26: 71112.
  • 26
    Posas, F., Wurgler-Murphy, S.M., Maeda, T., Witten, E.A., Thai, T.C., Saito, H. (1996) Yeast HOG1 MAP kinase cascade is regulated by a multistep phosphorelay mechanism in the SLN1–YPD1–SSK1 ‘two-component’ osmosensor. Cell 86: 865875.
  • 27
    Sambrook, J., Fritsch, E.F., Maniatis, T. (1989) Molecular Cloning: a Laboratory Manual. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press.
  • 28
    Stock, J.B., Ninfa, A.J., Stock, A.M. (1989) Protein phosphorylation and regulation of adaptive responses in bacteria. Microbiol Rev 53: 450490.
  • 29
    Surette, M.G., Miller, M.B., Bassler, B.L. (1999) Quorum sensing in Escherichia coli, Salmonella typhimurium, and Vibrio harveyi: a new family of genes responsible for autoinducer production. Proc Natl Acad Sci USA 96: 16391644.
  • 30
    Tokishita, S., Kojima, A., Mizuno, T. (1992) Transmembrane signal transduction and osmoregulation in Escherichia coli: functional importance of the transmembrane regions of membrane-localized protein kinase, EnvZ. J Biochem 111: 707713.
  • 31
    Uhl, M.A. & Miller, J.F. (1994) Autophosphorylation and phosphotransfer in the Bordetella pertussis BvgAS signal transduction cascade. Proc Natl Acad Sci USA 91: 11631167.
  • 32
    Uhl, M.A. & Miller, J.F. (1996) Central role of the BvgS receiver as a phosphorylated intermediate in a complex two-component phosphorelay. J Biol Chem 271: 3317633180.