• 1
    Atkin, A.L., Altamura, N., Leeds, P., Culbertson, M.R. (1995) The majority of yeast UPF1 co-localizes with polyribosomes in the cytoplasm. Mol Biol Cell 6: 611625.
  • 2
    Bardwell, L., Cook, J.G., Chang, E.C., Cairns, B.R., Thorner, J. (1996) Signaling in the yeast pheromone response pathway: specific and high-affinity interaction of the mitogen-activated protein (MAP) kinases Kss1 and Fus3 with the upstream MAP kinase kinase Ste7. Mol Cell Biol 16: 36373650.
  • 3
    Bardwell, L., Cook, J.G., Voora, D., Baggott, D.M., Martinez, A.R., Thorner, J. (1998) Repression of yeast Ste12 transcription factor by direct binding of unphosphorylated Kss1 MAPK and its regulation by the Ste7 MEK. Genes Dev 12: 28872898.
  • 4
    Boeke, J.D. & Sandmeyer, S.B. (1991) Yeast transposable elements. In The Molecular and Cellular Biology of the Yeast Saccharomyces. Broach, J.R., Pringle, J., and Jones, E. (eds). Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press. pp. 193262.
  • 5
    Boeke, J.D., LaCroute, F., Fink, G.R. (1984) A positive selection for mutants lacking orotidine-5′-phosphate decarboxylase activity in yeast: 5-fluoro-orotic acid resistance. Mol Gen Genet 197: 345346.
  • 6
    Brill, J.A., Elion, E.A., Fink, G.R. (1994) A role for autophosphorylation revealed by activated alleles of FUS3, the yeast MAP kinase homolog. Mol Biol Cell 5: 297312.
  • 7
    Chang, F. & Herskowitz, I. (1990) Identification of a gene necessary for cell cycle arrest by a negative growth factor of yeast: FAR1 is an inhibitor of a G1 cyclin, CLN2. Cell 63: 9991011.
  • 8
    Chapman, K.B. & Boeke, J.D. (1991) Isolation and characterization of the gene encoding yeast debranching enzyme. Cell 65: 483492.
  • 9
    Company, M., Adler, C., Errede, B. (1988) Identification of a Ty1 regulatory sequence responsive to STE7 and STE12. Mol Cell Biol 8: 25452554.
  • 10
    Conte, Jr, D., Barber, E., Banerjee, M., Garfinkel, D.J., Curcio, M.J. (1998) Posttranslational regulation of Ty1 retrotransposition by mitogen-activated protein kinase Fus3. Mol Cell Biol 18: 25022513.
  • 11
    Cook, J.G., Bardwell, L., Kron, S.J., Thorner, J. (1996) Two novel targets of the MAP kinase Kss1 are negative regulators of invasive growth in the yeast Saccharomyces cerevisiae. Genes Dev 10: 28312848.
  • 12
    Cook, J.G., Bardwell, L., Thorner, J. (1997) Inhibitory and activating functions for MAPK Kss1 in the S. cerevisiae filamentous-growth signalling pathway. Nature 390: 8588.
  • 13
    Curcio, M.J. & Garfinkel, D.J. (1991) Single-step selection for Ty1 element retrotransposition. Proc Natl Acad Sci USA 88: 936940.
  • 14
    Curcio, M.J. & Garfinkel, D.J. (1994) Heterogeneous functional Ty1 elements are abundant in the Saccharomyces cerevisiae genome. Genetics 136: 12451259.
  • 15
    Curcio, M.J. & Garfinkel, D.J. (1999) New lines of host defense: inhibition of retrotransposition by Fus3p and NER/TFIIH. Trends Genet 15: 4345.DOI: 10.1016/s0168-9525(98)01643-6
  • 16
    Drake, J.W. (1991) A constant rate of spontaneous mutation in DNA-based microbes. Proc Natl Acad Sci USA 88: 71607164.
  • 17
    Eichinger, D.J. & Boeke, J.D. (1988) The DNA intermediate in yeast Ty1 element transposition copurifies with virus-like particles: cell-free Ty1 transposition. Cell 54: 955966.
  • 18
    Elion, E.A., Brill, J.A., Fink, G.R. (1991) Functional redundancy in the yeast cell cycle: FUS3 and KSS1 have both overlapping and unique functions. Cold Spring Harbor Symp Quant Biol 56: 4149.
  • 19
    Elion, E.A., Satterberg, B., Kranz, J.E. (1993) FUS3 phosphorylates multiple components of the mating signal transduction cascade: evidence for STE12 and FAR1. Mol Biol Cell 4: 495510.
  • 20
    Errede, B. (1993) MCM1 binds to a transcriptional control element in Ty1. Mol Cell Biol 13: 5762.
  • 21
    Errede, B. & Ammerer, G. (1989) STE12, a protein involved in cell-type-specific transcription and signal transduction in yeast, is part of protein–DNA complexes. Genes Dev 3: 13491361.
  • 22
    Errede, B., Company, M., Ferchak, J.D., Hutchison, C.A.D., Yarnell, W.S. (1985) Activation regions in a yeast transposon have homology to mating type control sequences and to mammalian enhancers. Proc Natl Acad Sci USA 82: 54235427.
  • 23
    Errede, B., Gartner, A., Zhou, Z., Nasmyth, K., Ammerer, G. (1993) MAP kinase-related FUS3 from S. cerevisiae is activated by STE7 in vitro. Nature 362: 261264.
  • 24
    Farley, F.W., Satterberg, B., Goldsmith, E.J., Elion, E.A. (1999) Relative dependence of different outputs of the Saccharomyces cerevisiae pheromone response pathway on the MAP kinase Fus3p. Genetics 151: 14251444.
  • 25
    Garrett, J.M. (1997) The control of morphogenesis in Saccharomyces cerevisiae by Elm1 kinase is responsive to RAS/cAMP pathway activity and tryptophan availability. Mol Microbiol 26: 809820.
  • 26
    Gartner, A., Nasmyth, K., Ammerer, G. (1992) Signal transduction in Saccharomyces cerevisiae requires tyrosine and threonine phosphorylation of FUS3 and KSS1. Genes Dev 6: 12801292.
  • 27
    Gavrias, V., Andrianopoulos, A., Gimeno, C.J., Timberlake, W.E. (1996) Saccharomyces cerevisiae TEC1 is required for pseudohyphal growth. Mol Microbiol 19: 12551263.
  • 28
    Guldener, U., Heck, S., Fielder, T., Beinhauer, J., Hegemann, J.H. (1996) A new efficient gene disruption cassette for repeated use in budding yeast. Nucleic Acids Res 24: 25192524.
  • 29
    Hall, J.P., Cherkasova, V., Elion, E., Gustin, M.C., Winter, E. (1996) The osmoregulatory pathway represses mating pathway activity in Saccharomyces cerevisiae: isolation of a FUS3 mutant that is insensitive to the repression mechanism. Mol Cell Biol 16: 67156723.
  • 30
    Jordan, I.K. & McDonald, J.F. (1999) Tempo and mode of Ty element evolution in Saccharomyces cerevisiae. Genetics 151: 13411351.
  • 31
    Kenna, M.A., Brachmann, C.B., Devine, S.E., Boeke, J.D. (1998) Invading the yeast nucleus: a nuclear localization signal at the C terminus of Ty1 integrase is required for transposition in vivo. Mol Cell Biol 18: 11151124.
  • 32
    Kim, J.M., Vanguri, S., Boeke, J.D., Gabriel, A., Voytas, D.F. (1998) Transposable elements and genome organization: a comprehensive survey of retrotransposons revealed by the complete Saccharomyces cerevisiae genome sequence. Genome Res 8: 464478.
  • 33
    Kron, S.J., Styles, C.A., Fink, G.R. (1994) Symmetric cell division in pseudohyphae of the yeast Saccharomyces cerevisiae. Mol Biol Cell 5: 10031022.
  • 34
    Laloux, I., Dubois, E., Dewerchin, M., Jacobs, E. (1990) TEC1, a gene involved in the activation of Ty1 and Ty1-mediated gene expression in Saccharomyces cerevisiae: cloning and molecular analysis. Mol Cell Biol 10: 35413550.
  • 35
    Laloux, I., Jacobs, E., Dubois, E. (1994) Involvement of SRE element of Ty1 transposon in TEC1-dependent transcriptional activation. Nucleic Acids Res 22: 9991005.
  • 36
    Lee, B.S., Lichtenstein, C.P., Faiola, B., Rinckel, L.A., Wysock, W., Curcio, M.J., Garfinkel, D.J. (1998) Posttranslational inhibition of Ty1 retrotransposition by nucleotide excision repair/transcription factor TFIIH subunits Ssl2p and Rad3p. Genetics 148: 17431761.
  • 37
    Liu, H., Styles, C.A., Fink, G.R. (1993) Elements of the yeast pheromone response pathway required for filamentous growth of diploids. Science 262: 17411744.
  • 38
    Madhani, H.D. & Fink, G.R. (1997) Combinatorial control required for the specificity of yeast MAPK signaling. Science 275: 13141317.
  • 39
    Madhani, H.D., Styles, C.A., Fink, G.R. (1997) MAP kinases with distinct inhibitory functions impart signaling specificity during yeast differentiation. Cell 91: 673684.
  • 40
    Moore, S.P., Rinckel, L.A., Garfinkel, D.J. (1998) A Ty1 integrase nuclear localization signal required for retrotransposition. Mol Cell Biol 18: 11051114.
  • 41
    Mosch, H.U. & Fink, G.R. (1997) Dissection of filamentous growth by transposon mutagenesis in Saccharomyces cerevisiae. Genetics 145: 671684.
  • 42
    Mosch, H.U., Roberts, R.L., Fink, G.R. (1996) Ras2 signals via the Cdc42/Ste20/mitogen-activated protein kinase module to induce filamentous growth in Saccharomyces cerevisiae. Proc Natl Acad Sci USA 93: 53525356.
  • 43
    Oehlen, L. & Cross, F.R. (1998) The mating factor response pathway regulates transcription of TEC1, a gene involved in pseudohyphal differentiation of Saccharomyces cerevisiae. FEBS Lett 429: 8388.DOI: 10.1016/s0014-5793(98)00568-7
  • 44
    O'rourke, S.M. & Herskowitz, I. (1998) The Hog1 MAPK prevents cross talk between the HOG and pheromone response MAPK pathways in Saccharomyces cerevisiae. Genes Dev 12: 28742886.
  • 45
    Pan, X.W. & Heitman, J. (1999) Cyclic AMP-dependent protein kinase regulates pseudohyphal differentiation in Saccharomyces cerevisiae. Mol Cell Biol 19: 48744887.
  • 46
    Peter, M. & Herskowitz, I. (1994) Direct inhibition of the yeast cyclin-dependent kinase Cdc28-Cln by Far1. Science 265: 12281231.
  • 47
    Roberts, R.L. & Fink, G.R. (1994) Elements of a single MAP kinase cascade in Saccharomyces cerevisiae mediate two developmental programs in the same cell type: mating and invasive growth. Genes Dev 8: 29742985.
  • 48
    Rose, M.D., Winston, F., Hieter, P. (1990) Methods in Yeast Genetics. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press.
  • 49
    Sharon, G., Burkett, T.J., Garfinkel, D.J. (1994) Efficient homologous recombination of Ty1 element cDNA when integration is blocked. Mol Cell Biol 14: 65406551.
  • 50
    Stevenson, B.J., Rhodes, N., Errede, B., Sprague, Jr, G.F. (1992) Constitutive mutants of the protein kinase STE11 activate the yeast pheromone response pathway in the absence of the G protein. Genes Dev 6: 12931304.
  • 51
    Tedford, K., Kim, S., Sa, D., Stevens, K., Tyers, M. (1997) Regulation of the mating pheromone and invasive growth responses in yeast by two MAP kinase substrates. Curr Biol 7: 228238.
  • 52
    Vallejo, A.N., Pogulis, R.J., Pease, L.R. (1995) Mutagenesis and synthesis of novel recombinant genes using PCR. In PCR Primer: a Laboratory Manual. Dieffenbach, C.W., and Dveksler, G.S. (eds). Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press, pp. 603612.
  • 53
    Wassmann, K. & Ammerer, G. (1997) Overexpression of the G1-cyclin gene CLN2 represses the mating pathway in Saccharomyces cerevisiae at the level of the MEKK Ste11. J Biol Chem 272: 1318013188.
  • 54
    Xu, H. & Boeke, J.D. (1991) Inhibition of Ty1 transposition by mating pheremones in Saccharomyces cerevisiae. Mol Cell Biol 11: 27362743.
  • 55
    Zhang, S., Burkett, T.J., Yamashita, I., Garfinkel, D.J. (1997) Genetic redundancy between SPT23 and MGA2: regulators of Ty-induced mutations and Ty1 transcription in Saccharomyces cerevisiae. Mol Cell Biol 17: 47184729.
  • 56
    Zhou, Z., Gartner, A., Cade, R., Ammerer, G., Errede, B. (1993) Pheromone-induced signal transduction in Saccharomyces cerevisiae requires the sequential function of three protein kinases. Mol Cell Biol 13: 20692080.