Aerobic and anaerobic microbiology of chronic venous ulcers
Article first published online: 5 JAN 2002
International Journal of Dermatology
Volume 37, Issue 6, pages 426–428, June 1998
How to Cite
Brook, I. and Frazier, E. H. (1998), Aerobic and anaerobic microbiology of chronic venous ulcers. International Journal of Dermatology, 37: 426–428. doi: 10.1046/j.1365-4362.1998.00445.x
- Issue published online: 5 JAN 2002
- Article first published online: 5 JAN 2002
Background The role of bacteria in the pathogenesis of chronic venous leg ulcers (CVLU) is unclear. The objective of the study was to establish the aerobic and anaerobic bacteriology of CVLU.
Methods A retrospective review was carried out of the clinical and microbiological laboratory records obtained from patients with CVLU. Microorganisms were grown from 43 specimens obtained from 41 patients.
Results Aerobic or facultative bacteria alone were present in 18 (42%) specimens, anaerobic bacteria only in three (7%), and mixed aerobic–anaerobic flora in 22 (51%).
In total, there were 97 isolates, 64 aerobic or facultative and 33 anaerobic, an average of 2.3 isolates per specimen (1.5 aerobes and 0.8 anaerobes). The predominant aerobic organisms were Staphylococcus aureus (26 isolates), group D streptococci (5), and Escherichia coli (5). The predominant anaerobes were Peptostreptococcus spp. (15), Bacteroides fragilis group (6), Propionibacterium acnes (4), and Prevotella spp. (3).
Conclusions CVLU have a polymicrobial aerobic–anaerobic flora.