Comparison of two surgical approaches for treating vitiligo: a preliminary study
Article first published online: 14 MAY 2002
International Journal of Dermatology
Volume 41, Issue 3, pages 135–138, March 2002
How to Cite
Özdemir, M., Çetinkale, O., Wolf, R., Kotoğyan, A., Mat, C., Tüzün, B. and Tüzün, Y. (2002), Comparison of two surgical approaches for treating vitiligo: a preliminary study. International Journal of Dermatology, 41: 135–138. doi: 10.1046/j.1365-4362.2002.01391.x
- Issue published online: 14 MAY 2002
- Article first published online: 14 MAY 2002
Background Surgical techniques have recently been introduced for patients with vitiligo. Randomized controlled trials have not been performed.
Aim To compare the efficacy and side-effects of two surgical methods (suction blister vs. thin split-thickness graft technique) for the treatment of vitiligo.
Methods Three suction blisters, approximately 0.8 cm in diameter, made with a special tool attached to a vacuum extractor, which were converted to erosions by removal of the roofs of the bullae, and one round erosion of approximately the same diameter, made using a silver knife, were created. One roof of a blister and two cutaneous thin split-thickness grafts taken from the gluteal region were transferred onto recipient vitiliginous areas; one was left alone. The results were evaluated by one non-blind and two blind observers bimonthly during the 3-month follow-up period.
Results Repigmentation rates were 25–65% in the suction blister technique and 90% in the thin split-thickness graft technique (P < 0.001).
Conclusions The thin split-thickness graft technique is superior to the suction blister technique in treating vitiligo.