Comparison of two surgical approaches for treating vitiligo: a preliminary study

Authors

  • Mustafa Özdemir MD,

    Corresponding author
    1. From the Departments of Dermatology and Plastic Surgery, Cerrahpaşa Medical Faculty, Istanbul University, Istanbul, Turkey, Sackler Medical Faculty, Ichilov Hospital, Tel Aviv, Israel, and Department of Dermatology, Medical Faculty, Trakya University, Edirne, Turkey
      Mustafa Özdemir, MD Hatice Sultan Mah. Muhtar Yekta Sokak Veziroğlu Apt. 11/6 Fatih Istanbul, 80200 Turkey E-mail: mustafaozdemir@yahoo.com
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  • Oğuz Çetinkale MD,

    1. From the Departments of Dermatology and Plastic Surgery, Cerrahpaşa Medical Faculty, Istanbul University, Istanbul, Turkey, Sackler Medical Faculty, Ichilov Hospital, Tel Aviv, Israel, and Department of Dermatology, Medical Faculty, Trakya University, Edirne, Turkey
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  • Ronni Wolf MD,

    1. From the Departments of Dermatology and Plastic Surgery, Cerrahpaşa Medical Faculty, Istanbul University, Istanbul, Turkey, Sackler Medical Faculty, Ichilov Hospital, Tel Aviv, Israel, and Department of Dermatology, Medical Faculty, Trakya University, Edirne, Turkey
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  • Agop Kotoğyan MD,

    1. From the Departments of Dermatology and Plastic Surgery, Cerrahpaşa Medical Faculty, Istanbul University, Istanbul, Turkey, Sackler Medical Faculty, Ichilov Hospital, Tel Aviv, Israel, and Department of Dermatology, Medical Faculty, Trakya University, Edirne, Turkey
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  • Cem Mat MD,

    1. From the Departments of Dermatology and Plastic Surgery, Cerrahpaşa Medical Faculty, Istanbul University, Istanbul, Turkey, Sackler Medical Faculty, Ichilov Hospital, Tel Aviv, Israel, and Department of Dermatology, Medical Faculty, Trakya University, Edirne, Turkey
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  • Binnur Tüzün MD,

    1. From the Departments of Dermatology and Plastic Surgery, Cerrahpaşa Medical Faculty, Istanbul University, Istanbul, Turkey, Sackler Medical Faculty, Ichilov Hospital, Tel Aviv, Israel, and Department of Dermatology, Medical Faculty, Trakya University, Edirne, Turkey
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  • Yalçın Tüzün MD

    1. From the Departments of Dermatology and Plastic Surgery, Cerrahpaşa Medical Faculty, Istanbul University, Istanbul, Turkey, Sackler Medical Faculty, Ichilov Hospital, Tel Aviv, Israel, and Department of Dermatology, Medical Faculty, Trakya University, Edirne, Turkey
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Mustafa Özdemir, MD Hatice Sultan Mah. Muhtar Yekta Sokak Veziroğlu Apt. 11/6 Fatih Istanbul, 80200 Turkey E-mail: mustafaozdemir@yahoo.com

Abstract

Background Surgical techniques have recently been introduced for patients with vitiligo. Randomized controlled trials have not been performed.

Aim To compare the efficacy and side-effects of two surgical methods (suction blister vs. thin split-thickness graft technique) for the treatment of vitiligo.

Methods Three suction blisters, approximately 0.8 cm in diameter, made with a special tool attached to a vacuum extractor, which were converted to erosions by removal of the roofs of the bullae, and one round erosion of approximately the same diameter, made using a silver knife, were created. One roof of a blister and two cutaneous thin split-thickness grafts taken from the gluteal region were transferred onto recipient vitiliginous areas; one was left alone. The results were evaluated by one non-blind and two blind observers bimonthly during the 3-month follow-up period.

Results Repigmentation rates were 25–65% in the suction blister technique and 90% in the thin split-thickness graft technique (P < 0.001).

Conclusions The thin split-thickness graft technique is superior to the suction blister technique in treating vitiligo.

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