• 1
    NIH-NHLBI/WHO workshop report. Global strategy for asthma management and prevention. NIH publication 2002: O23659.
  • 2
    Szefler SJ. Altering the course of asthma: introduction. J Allergy Clin Immunol 2002;109: S519520.
  • 3
    ISAAC Steering Committee. Worldwide variations in the prevalence of asthma symptoms: the International Study of Asthma and Allergies in Childhood (ISAAC). The International Study of Asthma and Allergies in Childhood (ISAAC) Steering Committee. Eur Respir J 1998;12: 315335.
  • 4
    Sole D, Yamada E, Vana AT, Werneck G, Freitas SL, Sologuren MJ et al. International Study of Asthma and Allergies in Childhood (ISAAC): prevalence of asthma and asthma-related symptoms among Brazilian schoolchildren. J Investig Allerg Clin Immunol 2001;11: 123128.
  • 5
    Addo-Yobo EOD, Custovic A, Taggart SCO, Craven M, Bonnie B, Woodcock A. Risk factor for asthma in urban Ghana. Allergy Clin Immunol 2001;108: 363368.
  • 6
    MacIntyre UE, de Villiers FP, Owange-Iraka JW. Increase in childhood asthma admissions in urbanising population. S Afri Med J 2001;91: 667672.
  • 7
    Keeley DJ, Neill P, Gallivan S. Comparison of the prevalence of reversible airways obstruction in rural and urban Zimbabwean children. Thorax 1991;46: 549553.
  • 8
    Ng'ang'a LW, Odhiambo JÁ, Mungai MW. Prevalence of exercise-induced bronchospasm in Kenyan school children: an urban-rural comparison. Thorax 1998;53: 919926
  • 9
    Addo-Yobo EOD, Custovic A, Taggart SCO, Asafo-Agyei AP, Woodcock A. Exercise-induced bronchospasm in Ghana: differences in prevalence between urban and rural schoolchildren. Thorax 1997;52: 161165.
  • 10
    Faniran AO, Peat JK, Woolcock AJ. Prevalence of atopy, asthma symptoms and diagnosis and management of asthma: comparison of an affluent and non-affluent country. Thorax 1999;54: 606610.
  • 11
    Nriagu J, Robins T, Gary L, Liggans G, Davila R, Supuwood K et al. Prevalence of asthma and respiratory symptoms in south-central Durban, South Africa. Eur J Epidemiol 1999;15: 747755.
  • 12
    Melaku K, Berhane Y. Prevalence of wheezing and asthma-related symptoms among school children in Addis Ababa, Ethiopia. Ethiop Med J 1999;37: 247254.
  • 13
    Haby MM, Peat JK, Marks GB, Woolcock AJ, Leeder SR. Asthma in preschool children: prevalence and risk factors. Thorax 2001;56: 589595.
  • 14
    Ehrlich RI, Toit D, Jordaan E, Zwarenstein M, Potter P, Volmink JA et al. Risk factors for childhood asthma and wheezing. Importance of maternal and household smoking. Am J Respir Crit Care Med 1996;154: 681688.
  • 15
    Mohamed N, Ng'ang'al L, Odhiambo J, Nyamwaya J, Menzies R. Home environment and asthma in Kenyan schoolchildren: a case–control study. Thorax 1995;50: 7478.
  • 16
    Instituto Nacional de Estatística. Inquérito Demográfico e de Saúde. Mozambique: Relatório resumido, 1997.
  • 17
    Celedón JC, Soto-Quiros ME, Silverman EK, Hanson LA, Weiss ST. Risk factors for childhood asthma in Costa Rica. Chest 2001;120: 785790.
  • 18
    von Mutius E. Environmental factors influencing the development and progression of pediatric asthma. J Allergy Clin Immunol 2002;109: S525532.
  • 19
    von Mutius E. The environmental predictors of allergic disease. J Allergy Clin Immunol 2000;105: 919.
  • 20
    Martinez F. Role of viral infections in the inception of asthma and allergies during childhood: could they be protective? Thorax 1994;49: 11891191.
  • 21
    Wong GWK, Li ST, Hui DSC, Fok TF, Zhong NS, Chen YZ et al. Individual allergens as risk factors for asthma and bronchial hyperresponsiveness in Chinese children. Eur Respir J 2002;19: 288293.
  • 22
    Poyser MA, Nelson H, Ehrlich RI, Bateman ED, Parnell S, Puterman A et al. Socioeconomic deprivation and asthma prevalence and severity in young adolescents. Eur Respir J 2002;19: 892898.
  • 23
    Weiss ST. Environmental risk factors in childhood asthma. Clin Exp Allergy 1998;28: S5: 29–34.
  • 24
    Yemaneberhan H, Bekele Z, Venn A, Lewis S, Parry E, Britton J. Prevalence of wheeze and asthma and relation to atopy in urban and rural Ethiopia. Lancet 1997;350: 8590.
  • 25
    Perzanowski M, Ng'ang'a L, Carter M, Odhiambo J, Ngari P, Vaughan J et al. Atopy, asthma and antibodies to Ascaris among rural and urban children in Kenya. J Pediatr 2002;140: 582588.
  • 26
    Braun-Fahrländer C, Riedler J, Herz U, Eder W, Waser M, Grize L et al. Environmental exposure to endotoxin and its relation to asthma in school-age children. N Engl J Med 2002;347: 869877.
  • 27
    Powell CV, Nolan TM, Carlin JB, Bennett CM, Johnson PD. Respiratory symptoms and duration of residence in immigrant teenagers living in Melbourne, Australia. Arch Dis Child, 1999;81: 159162.
  • 28
    Martinez FD. Gene by environment interactions in the development of asthma. Clin Exp Allergy 1998;S5: 2125.
  • 29
    Tariq MS, Matthews SM, Hakim EA, Stevens M, Arshad SH, Hide DW. The prevalence of and risk factors for atopy in early childhood: a whole population birth cohort study. J Allergy Clin Immunol 1998;101: 587593.
  • 30
    Palmer L, Celedón J, Weiss S, Wang B, Fang Z, Xu X. Ascaris lumbricoides infection is associated with increased risk of childhood asthma and atopy in rural China. Am J Respir Crit Care Med 2002;165: 14891493
  • 31
    Van den Biggelaar AHJ, van Ree R, Rodriguez LC, Lell B, Deelder AM, Kremsner PG et al. Decreased atopy in children infected with Schistosoma haematobium: a role for parasite-induced interleukin-10. Lancet 2000;356: 17231727.
  • 32
    Yazdanbakhsh M, Kremsner PG, Van Ree Ronald A. Allergy, parasites, and the hygiene hypothesis. Science 2002;296: 490494
  • 33
    Scrivener S. Independent effects of intestinal parasite. Lancet 2001;358: 14931499.
  • 34
    Fagbule D, Ekanemee. Some environmental risk factors for childhood asthma: a case–control study. Ann Trop Paediatr 1994;14: 1519.
  • 35
    Wright AL, Holberg CJ, Taussig LM, Martinez FD. Factors influencing the relation of infant feeding to asthma and recurrent wheeze in childhood. Thorax 2001;56: 192197.
  • 36
    Wright AL, Holberg CJ, Taussig LM, Martinez FD. Relationship of infant feeding to recurrent wheezing at 6 years. Arch Pediatr Adolesc Med 1995;149: 758763.
  • 37
    Sears M, Greene M, Willan R, Taylor D, Flannery E, Cowan Jet al. Titre? Lancet 2002;360: 901907.
  • 38
    Oddy WH, Klerk NH, Sly PD, Holt PG. The effects of respiratory infections, atopy and breast feeding on childhood asthma. Eur Respir J 2002;19: 899905.