In part presented at the American Psychiatric Association Annual Meeting, Philadelphia, PA, May 18–23, 2002; NCDEU June 10–13, 2002, Boca Raton, FL; the European Stanley Foundation Meeting, Freiburg, Germany, September 12–14, 2002; and the 16th Annual Meeting of the International Group for the Study of Lithium-Treated Patients (IGSLI), Prague, Czech Republic, September 26–29, 2002.
Using technology to improve longitudinal studies: self-reporting with ChronoRecord in bipolar disorder
Article first published online: 3 FEB 2004
Volume 6, Issue 1, pages 67–74, February 2004
How to Cite
Bauer, M., Grof, P., Gyulai, L., Rasgon, N., Glenn, T. and Whybrow, P. C. (2004), Using technology to improve longitudinal studies: self-reporting with ChronoRecord in bipolar disorder. Bipolar Disorders, 6: 67–74. doi: 10.1046/j.1399-5618.2003.00085.x
The ChronoRecord Association is a non-profit organization that distributes ChronoRecord software at no charge to qualified clinicians (http://www.chronorecord.org). None of the authors have a financial interest in the ChronoRecord Association.
- Issue published online: 3 FEB 2004
- Article first published online: 3 FEB 2004
- Received 10 March 2003, revised and accepted for publication 4 September 2003
- bipolar disorder;
- ChronoRecord computer software;
- longitudinal studies;
Objectives: Longitudinal studies are an optimal approach to investigating the highly variable course and outcome associated with bipolar disorder, but are expensive and often have missing data. This study validates patient self-reported mood ratings using a home computer-based system (ChronoRecord) with clinician mood ratings on the Hamilton Depression Rating scale (HAMD) and Young Mania Rating scale (YMRS), and investigates the patient acceptance of the technology.
Methods: After brief training, outpatients with bipolar disorder were given the software version of an established paper based self-reporting form (ChronoSheet) to install on a home computer. Every day for 3 months, patients entered mood, medications, sleep, life events, and menstrual data. Weight was entered weekly.
Results: Eighty of 96 (83%) patients returned 8662 days of data. The mean days of data returned was 114.7 ± 32.3 SD The mean percentage of days missing for mood data was 6.1% ± 9.3 SD, equivalent to missing 7.3 day of the 114.7 days. Self-reported ratings were strongly correlated with clinician HAMD ratings (−0.683, p < 0.001).
Conclusions: This study demonstrates concurrent validity between ChronoRecord and HAMD. Patients with bipolar disorder showed high acceptance of a computer-based system for self-reporting of daily data. Automation of data collection can reduce missing data and eliminate errors associated with data entry. This technology also enables on-going feedback for both patient and researcher during a long-term study.