• Caballero, A., Cusi, E.,García, C. & García-Dorado, A. 2002. Accumulation of deleterious mutations: further D. melanogaster estimates and a simulation of the effects of selection. Evolution, in press.
  • Chavarrías, D., López Fanjul, C. & García-Dorado, A. 2001. The rate of mutation and the homozygous and heterozygous effects for competitive viability: a long-term experiment with Drosophila melanogaster. Genetics 158: 681693.
  • Crow, J.F. & Simmons, M.J. 1983. The mutation load in Drosophila. In: The Genetics and Biology of Drosophila (M.Ashburner, H. L.Carson & J. N.Thomson, eds), vol. 3c, pp. 1–35 . Academic Press, London.
  • Davies, E.K., Peters, A.D. & Keightley, P.D. 1999. High frequency of cryptic deleterious mutations in Caenorhabditis elegans. Science 285: 17481751.
  • Fernández, J. & López-Fanjul, C. 1996. Spontaneous mutational variances and covariances for fitness-related traits in Drosophila melanogaster. Genetics 143: 829837.
  • García-Dorado, A. 1997. The rate and effects distribution of viability mutations in Drosophila melanogaster. Evolution 51: 11301139.
  • García-Dorado, A. & Caballero, A. 2000. On the average degree of dominance of deleterious spontaneous mutations. Genetics 155: 19912001.
  • García-Dorado, A., Fernández, J. & López-Fanjul, C. 2000. Temporal uniformity of the spontaneous mutational variance of quantitative traits in Drosophila melanogaster. Genet. Res. 75: 4751.DOI: 10.1017/S0016672399004267
  • García-Dorado, A., López-Fanjul, C. & Caballero, A. 1999. Properties of spontaneous mutations affecting quantitative traits. Genet. Res. 74: 341350.DOI: 10.1017/S0016672399004206
  • García-Dorado, A., Monedero, J.L. & López-Fanjul, C. 1998. The mutation rate and the distribution of mutational effects of viability and fitness in Drosophila melanogaster. Genetica 102/103: 255265.
  • Houle, D., Hoffmaster, D.K., Charlesworth, B. & Assimacopoulos, S. 1992. The genomic mutation rate for fitness in Drosophila. Nature 359: 5860.
  • Houle, D., Hughes, K.A., Hoffsmaster, D.K., Ihara, J., Assimacopoulos, S., Canada, D. & Charlesworth, B. 1994. The effects of spontaneous mutation on quantitative traits. I. Variances and covariances of life history traits. Genetics 138: 773785.
  • Keightley, P.D. & Eyre-Walker, A. 1999. Terumi Mukai and the riddle of deleterious mutation rates. Genetics 153: 515523.
  • Kimura, M. 1962. On the probability of fixation of mutant genes in a population. Genetics 47: 713719.
  • Kondrashov, A. 1988. Deleterious mutation and the evolution of sexual reproduction. Nature 336: 435440.
  • Lynch, M., Blanchard, J., Houle, D., Kibota, T., Schultz, S., Vassilieva, L. & Willis, J. 1999. Spontaneous deleterious mutation. Evolution 53: 645663.
  • Lynch, M., Conery, J. & Bürger, R. 1995. Mutation accumulation and the extinction of small populations. Am. Nat. 146: 489518.
  • Mukai, T., Chigusa, S.I., Mettler, L.E. & Crow, J.F. 1972. Mutation rate and dominance of genes affecting viability in Drosophila melanogaster. Genetics 72: 333355.