SEARCH

SEARCH BY CITATION

References

  • 1
    Lynch, D.V. (1993) Sphingolipids. In Lipid Metabolism in Plants (Thomas, S, Moore, J., eds), pp. 286308. CRC Press, Inc, Boca Raton, FL.
  • 2
    Merrill, A.H.J., Schmelz, E.M., Wang, E., Dillehay, D.L., Rice, L.G., Meredith, F. & Riley, R.T. (1997) Importance of sphingolipids and inhibitors of sphingolipid metabolism as components of animal diets. J. Nutrition 127, 830S833S.
  • 3
    Post-Beittenmiller, D. (1996) Biochemistry and molecular biology of wax production in plants. Ann. Rev. Plant Phys. Plant Mol. Biol. 47, 405430.
  • 4
    Downey, R.K. & Röbbelen, G. (1989) Brassica species. In Oil Crops of the World (Röbbelen, G., Downey, R.K and Ashri, A., eds) , pp. 339362. McGraw-Hill, Inc, New York, NY.
  • 5
    Fehling, E. & Mukherjee, K.D. (1991) Acyl-CoA elongase from a higher plant (Lunaria annua): metabolic intermediates of very-long-chain acyl-CoA products and substrate specificity. Biochim. Biophys. Acta. 1082, 239246.
  • 6
    Suneja, S.K., Nagi, M.N., Cook, L. & Cinti, D.L. (1991) Decreased long-chain fatty acyl coenzyme A elongation activity in quaking and jimpy mouse brain: deficiency in one enzyme or multiple enzyme activities? J. Neurochem. 57, 140146.
  • 7
    Millar, A.A. & Kunst, L. (1997) Very-long-chain fatty acid biosynthesis is controlled through the expression and specificity of the condensing enzyme. Plant J. 12, 121131.
  • 8
    James, J.D.W., Lim, E., Keller, J., Plooy, I., Ralston, E. & Dooner, H.K. (1995) Directed tagging of the Arabidopsis fatty acid elongation1 (FAE1) gene with maize transposon activator. Plant Cel. 7, 309319.
  • 9
    Todd, J., Post-Beittenmiller, D. & Jaworski, J.G. (1999) KCS1 encodes a fatty acid elongase 3-ketoacyl-CoA synthase affecting wax biosynthesis in Arabidopsis thaliana. Plant J. 17, 119130.
  • 10
    Lessire, R., Bessoule, J.-J. & Cassagne, C. (1985) Solubilization of C18-CoA and C20-CoA elongases from Allium porrum L. epidermal cell microsomes. FEBS Lett. 187, 314320.
  • 11
    Fehling, E., Lessire, R., Cassagne, C. & Mukherjee, K.D. (1992) Solubilization and Partial Purification of Constituents of Acyl-CoA Elongase from Lunaria annua. Biochim. Biophys. Acta. 1126, 8894.
  • 12
    Imai, H., Hlousek-Radojcic, A., Matthis, A. & Jaworski, J. (1994) Elongation system involved in the biosynthesis of very long chain fatty acids in Brassica napus seeds: characterization and solubilization. In Plant Lipids Metabolism (Kader, J.-C & Mazliak, P., eds), pp. 118120. Kluwer Academic Publishers, Dordrecht, the Netherlands.
  • 13
    Lassner, M.W., Lardizabal, K. & Metz, J.G. (1996) A jojoba β-ketoacyl-CoA synthase cDNA complements the canola fatty acid elongation mutation in transgenic plants. Plant Cell 8, 281292.
  • 14
    Evenson, K.J. & Post-Beittenmiller, D. (1995) Fatty acid-elongating activity in rapidly expanding leek epidermis. Plant Physiol. 109, 707716.
  • 15
    Lessire, R., Bessoule, J.-J. & Cassagne, C. (1989) Involvement of a β-ketoacyl-CoA intermediate in acyl-CoA elongation by an acyl-CoA elongase purified from leek epidermal cells. Biochim. Biophys. Acta 1006, 3540.
  • 16
    Martin, C.R. (1993) Structure, function, and regulation of the chalcone synthase. International Review of Cytology – a Survey of Cell Biology, Vol. 147 (Jeon, K.W. & Jarvik, J., eds), pp. 233284. Academic Press Inc, San Diego, CA, USA.
  • 17
    Tai, H.Y. & Jaworski, J.G. (1993) 3-Ketoacyl-acyl carrier protein synthase-iii from spinach (Spinacia oleracea) is not similar to other condensing enzymes of fatty acid synthase. Plant Physiol. 103, 13611367.
  • 18
    Tsay, J.T., Oh, W., Larson, T.J., Jackowski, S.. & Rock, C.O. (1992) Isolation and characterization of the β-ketoacyl-acyl carrier protein synthase-III gene (fab H) from Escherichia coli K-12. J.Biol. Chem. 267, 68076814.
  • 19
    Ferrer, J.L., Jez, J.M., Bowman, M.E., Dixon, R.A. & Noel, J.P. (1999) Structure of chalcone synthase and the molecular basis of plant polyketide biosynthesis. Nat. Struct. Biol. 6, 775784.
  • 20
    Huang, W.J., Jia, J., Edwards, P., Dehesh, K., Schneider, G. & Lindqvist, Y. (1998) Crystal structure of β-ketoacyl-acyl carrier protein synthase II from E. coli reveals the molecular architecture of condensing enzymes. EMBO J. 17, 11831191.
  • 21
    Olsen, J.G., Kadziola, A., von Wettstein-Knowles, P., Siggaard-Andersen, M., Lindquist, Y. & Larsen, S. (1999) The X-ray crystal structure of β-ketoacyl [acyl carrier protein] synthase I. FEBS Lett. 460, 4652.
  • 22
    Qiu, X.Y., Janson, C.A., Konstantinidis, A.K., Nwagwu, S., Silverman, C., Smith, W.W., Khandekar, S., Lonsdale, J. & Abdel-Meguid, S.S. (1999) Crystal structure of β-ketoacyl-acyl carrier protein synthase III – a key condensing enzyme in bacterial fatty acid biosynthesis. J. Biol. Chem. 274, 3646536471.
  • 23
    Davies, C., Heath, R.J., White, S.W. & Rock, C.O. (2000) The 1.8 _ crystal structure and active-site architecture of β-ketoacyl-acyl carrier protein synthase III (FabH) from Escherichia coli. Structure 8, 185195.
  • 24
    Jez, J.M., Ferrer, J.-L., Bowman, M.E., Dixon, R.A. & Noel, J.P. (2000) Dissection of malonyl-Coenzyme A decarboxylation from polyketide formation in the reaction mechanism of a plant polyketide synthase. Biochemistry 39, 890902.
  • 25
    Ghanevati, M. & Jaworski, J.G. (2001) Active-site residues of a plant membrane-bound fatty acid elongase β-ketoacyl-CoA synthase, FAE1 KCS. Biochim. Biophys. Acta 1530, 7785.
  • 26
    Roughan, G. (1994) A semi-preparative enzymic synthesis of malonyl-CoA from [C-14]acetate and (CO2)-C-14: labelling in the 1, 2 or 3 position. Biochem. J. 300, 355358.
  • 27
    Ho, S.N., Hunt, H.D., Horton, R.M., Pullen, J.K. & Pease, L.R. (1989) Site-directed mutagenesis by overlap extension using the polymerase chain reaction. Gene 77, 5159.
  • 28
    Gietz, R.D. & Woods, R.A. (1994) High efficiency transformation in yeast. In Molecular Genetics of Yeast: Practical Approaches. (Johnston, J.A., ed.), pp. 121134. Oxford University Press, Oxford, UK.
  • 29
    Bradford, M.M. (1976) A rapid and sensitive method of quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72, 248254.
  • 30
    Laemmli, U.K. (1970) Cleavage of structural proteins during theassembly of the head of bacteriophage T4. Nature 227, 680685.
  • 31
    Kyhse-Andersen, J. (1984) Electroblotting of multiple gels: a simple apparatus without buffer tank for rapid transfer of proteins from polyacrylamide to nitrocellulose. J. Biochem. Biophys. Methods 10, 203209.
  • 32
    Harlow, E. & Lane, D. (1988) Antibodies: A Laboratory Manual, Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY, USA.
  • 33
    Hochstrasser, D.F., Patchornik, A. & Merril, C.P. (1988) Development of polyacrylamide gels that improve the separation of proteins and their detection by silver staining. Anal. Biochem. 173, 412423.
  • 34
    Garwin, J.L., Klages, A.L. & Cronan, J.E. (1980) Jr Structural, enzymatic, and genetic studies of β-ketoacyl-acyl carrier protein synthases I and II of Escherichia coli. J. Biol. Chem. 255, 1194911956.
  • 35
    Persson, B. & Argos, P. (1994) Prediction of transmembrane segments in proteins utilising multiple sequence alignments. J. Mol. Biol. 237, 182192.
  • 36
    Emanuelsson, O., Nielsen, H., Brunak, S. & von Heijne, G. (2000) Predicting subcellular localization of proteins based on their N-terminal amino acid sequence. J. Mol. Biol. 300, 10051016.
  • 37
    Agrawal, V., Lessire, R. & Stumpf, P. (1984) Biosynthesis of very long chain fatty acids in microsomes from epidermal cells of Allium porrum L. Arch. Biochem. Biophys. 230, 580589.
  • 38
    Agrawal, V. & Stumpf, P. (1985) Characterization and solubilization of an acyl chain elongation system in microsomes of leek epidermal cells. Arch. Biochem. Biophys. 240, 154165.
  • 39
    Kresze, G.-B., Steber, L., Oesterhelt, D. & Lynen, F. (1977) Reaction of yeast fatty acid synthetase with iodoacetamide. 2. Identification of the amino acid residues reacting with iodoacetamide and primary structure of a peptide containing the peripheral sulfhydryl group. Eur. J. Biochem. 79, 181190.
  • 40
    Witkowski, A., Joshi, A.K., Lindqvist, Y. & Smith, S. (1999) Conversion of a β-ketoacyl synthase to a malonyl decarboxylase by replacement of the active-site cysteine with glutamine. Biochemistry 39, 1164311650.
  • 41
    Jez, J.M. & Noel, J.P. (2000) Mechanism of chalcone synthase: pKa of the catalytic cysteine and the role of the conserved histidine in a plant polyketide synthase. J. Biol. Chem. 275, 3964039646.