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Leptin, body fat content and energy expenditure in intact and gonadectomized adult cats: a preliminary study
Article first published online: 20 DEC 2001
DOI: 10.1046/j.1439-0396.2001.00322.x
Issue
1439-0396/asset/cover.gif?v=1&s=781026e2abd8b84efb2bbcc23b2b8fdcf69e8e4c "Journal of Animal Physiology and Animal Nutrition")
Journal of Animal Physiology and Animal Nutrition
Volume 85, Issue 7-8, pages 195–199, August 2001
Additional Information
How to Cite
Martin, L. , Siliart, B. , Dumon, H. , Backus, R. , Biourge, V. and Nguyen, P. (2001), Leptin, body fat content and energy expenditure in intact and gonadectomized adult cats: a preliminary study. Journal of Animal Physiology and Animal Nutrition, 85: 195–199. doi: 10.1046/j.1439-0396.2001.00322.x
Publication History
- Issue published online: 20 DEC 2001
- Article first published online: 20 DEC 2001
- Abstract
- Article
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The present study was conducted to assess the body composition, leptin, and energy expenditure changes following gonadectomy in cats. Twenty-one females (12 intact and nine spayed) and 21 males (11 intact and 10 castrated) were used. Body weight was recorded. Serum plasma leptin was measured by radioimmunoassay and body composition and energy expenditure were assessed after injection of doubly labelled water. These results confirmed the gain in body weight and body fat following neutering and demonstrated a strong linear relationship between body fat and serum level of leptin. Energy expenditure decreased in castrated cats in comparison with intact ones. This study underlined the effect of gonadectomy as a major factor of obesity in cats and showed that the increase in circulating leptin reflected the amount of body fat. The present results provide further evidence that the regimen of gonadectomized cats should be carefully controlled to avoid excessive weight gain.