VFH Chong FRCR; Y-F Fan FRCR.
Meningeal infiltration in recurrent nasopharyngeal carcinoma
Article first published online: 24 DEC 2001
Volume 44, Issue 1, pages 23–27, February 2000
How to Cite
Chong, V. F. and Fan, Y.-F. (2000), Meningeal infiltration in recurrent nasopharyngeal carcinoma. Australasian Radiology, 44: 23–27. doi: 10.1046/j.1440-1673.2000.00767.x
- Issue published online: 24 DEC 2001
- Article first published online: 24 DEC 2001
- foramen magnum;
- jugular foramen;
- recurrent nasopharyngeal carcinoma
Permeative infiltration of the meninges appears to be a distinct form of recurrent nasopharyngeal carcinoma (NPC). The present report of eight patients with recurrent NPC illustrates meningeal infiltration following basal foramina extension. Seven of the eight patients (88%) showed jugular foramen involvement. Three patients had concomitant infiltration of the foramen magnum. There was one patient showing spread through the foramen lacerum. Only four (50%) of these patients had clinically detectable tumour in the nasopharynx, while the other half showed deep submucosal recurrence with endoscopically unremarkable findings. Permeative meningeal infiltration appears to be a distinct form of NPC recurrence. It is important to recognize this phenomenon so as to optimize the treatment options.