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Impact of alcohol on the ability of Kupffer cells to produce chemokines and its role in alcoholic liver disease
Article first published online: 25 DEC 2001
DOI: 10.1046/j.1440-1746.2000.02174.x
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How to Cite
Bautista, A. P. (2000), Impact of alcohol on the ability of Kupffer cells to produce chemokines and its role in alcoholic liver disease. Journal of Gastroenterology and Hepatology, 15: 349–356. doi: 10.1046/j.1440-1746.2000.02174.x
Publication History
- Issue published online: 25 DEC 2001
- Article first published online: 25 DEC 2001
REFERENCES
- 1& Flow cytometric and immunohistochemical evaluation of ethanol-induced changes in splenic and thymic lymphoid cell populations. Alcohol. Clin. Exp. Res. 1991; 15: 796 803.Direct Link:
- 2, , et al. Ethanol-induced CD3 and CD2 hyporesponsiveness of peripheral blood T-lymphocytes. Immunopharmacol. Immunotoxicol. 1992; 14: 939 53.
- 3The role of Kupffer cells in the induction of hepatotoxicity and immunosuppression in chronic alcoholic rats. In: Wisse E, Knook DL, Wake K, eds. Cells of the Hepatic Sinusoid, vol. 5. Leiden: Kupffer Cell Foundation, 1995; 70 1.
- 4, , , The impact of alcohol on the free radical formation and chemokine release by Kupffer cells: The role of tolerance, iron and HIV-1. In: Knook DL, Wisse E, Fraser R, eds. Cells of the Hepatic Sinusoids, Volume 7. Leiden: Kupffer Cell Foundation, 1998; 90 5.
- 5, , A comparison of lipopolysaccharide-induced hepatitis in ethanol-fed Wistar and Lewis rats. Alcohol. Clin. Exp. Res. 1998; 22: 1525 30.Direct Link:
- 6, , et al. Alcohol causes both tolerance and sensitization of rat Kupffer cells via mechanisms dependent on endotoxin. Gastroenterology 1998; 115: 443 51.
- 7Chronic alcohol intoxication attenuates human immunodeficiency virus-1 glycoprotein 120-induced superoxide anion release by isolated Kupffer cells. Alcohol. Clin. Exp. Res. 1998; 22: 474 80.Direct Link:
- 8Role of Kupffer cells and reactive oxygen species in hepatic injury during acute and chronic alcohol intoxication. Alcohol. Clin. Exp. Res. 1998; 22: S255 9.Direct Link:
- 9Chronic alcohol intoxication induces hepatic injury through enhanced macrophage inflammatory protein-2 production and intercellular adhesion molecule-1 expression in the liver. Hepatology 1997; 25: 335 42.Direct Link:
- 10& Immune reactivity to proteins biotransformed by alcohol metabolites. Alcohol. Clin. Exp. Res. 1998; 22: S204 7.
- 11Chronic alcohol intoxication suppresses anti-HIV-1 antibody production and antigen presentation by murine hepatic non-parenchymal cells. Alcohol. Clin. Exp. Res. 1999; 23 (Suppl): 120.
- 12, , et al. Kinetics of IL-8, MIP-1, TNFα, IL-1β, IL-ra and IL-10 in human whole blood samples triggered by smooth and rough LPS. Microbiologica. 1998; 21: 123 30.
- 13, , , Regulation of gene expression of chemokines and their receptors. In: Kownatzki E, Norgauer J, eds. Chemokines and Skin. Basel: Birkhäuser Verlag, 1998; 37 56.
- 14, , , Tumor necrosis factor and alcoholic liver disease. Alcohol. Clin. Exp. Res. 1998; 22: S248 52.Direct Link:
- 15, , , Chemokine levels in human liver homogenates; associations between GRO alpha and histopathological evidence of alcoholic hepatitis. Hepatology 1996; 24: 1156 60.
- 16, , et al. Distinct patterns of chemokine expression are associated with leukocyte recruitment in alcoholic hepatitis and alcoholic cirrhosis. J. Pathol. 1998; 186: 82 9.Direct Link:
- 17& Acute alcohol intoxication and gadolinium chloride attenuate lipopolysaccharide-induced CC-chemokine release in vivo. Alcohol 2000; 20: 1 11.
- 18Macrophage inflammatory proteins: Biology and role in pulmonary inflammation. Exp. Lung Res. 1994; 20: 273 90.
- 19, , Kinetics of transcription factors regulating RANTES chemokine gene reveal a developmental switch in nuclear events during T-lymphocyte activation. Mol. Cell. Biol. 1996; 16: 202 10.
- 20, , , , Ethanol-induced expression of cytokines in a first-trimester trophoblast cell line. Am. J. Obs. Gynecol. 1998; 179: 470 5.
- 21Production of macrophage inflammatory protein-2 (MIP2) by Kupffer cells and upregulation of adhesion molecule expression promote hepatic injury in chronic alcoholic rats . In: Wisse E, Knook DL, Balabaud C, eds. Cells of the Hepatic Sinusoids, Vol. 6. Leiden: Kupffer Cell Foundation, 1997; 272 5.
- 22, , et al. Production of chemotactic factor, IL-8, from hepatocytes exposed to ethanol. Hepatology 1993; 18: 1477 82.Direct Link:
- 23, , Generation of a CD11b/c upregulating and chemotactic factor by hepatocytes of endotoxic rats: Nonidentity with interleukin-8. Shock 1994; 2: 332 5.
- 24, , , , Interferon-inducible protein involves vascular smooth muscle migration. J. Biol. Chem. 1996; 271: 24 286 93.
- 25& Neutrophil-activating protein ENA-78 and IL-8 exhibit different patterns of expression in lipopolysaccharide- and cytokine-stimulated human monocytes. J. Immunol. 1997; 158: 3888 94.
- 26, , , , Cytokine RANTES released by thrombin-stimulated platelets is a potent attractant for human eosinophils. J. Exp. Med. 1992; 176: 587 92.
- 27, , et al. Macrophages secrete a novel heparin binding protein with inflammatory and neutrophil chemokinetic properties. J. Exp. Med. 1988; 167: 570 81.
- 28, , , Elimination of macrophages by liposome-encapsulated dimethylene diphosphonate suppresses the endotoxin-induced priming of Kupffer cells. J. Leuk. Biol. 1994; 55: 321 7.
- 29, , , LPS-mediated NF-κB activation in rat Kupffer cells can be induced independently of CD14. Am. J. Physiol. 1996; 270: G956 61.
- 30& CD11c/CD18, a transmembrane signaling receptor for lipopolysaccharide. J. Exp. Med. 1995; 181: 1473 9.
- 31, , , , Antineutrophil antibody (1F12) alters superoxide release by neutrophils and Kupffer cells. J. Leuk. Biol. 1994; 55: 328 35.
- 32& Intracellular signaling network as a target for ethanol. Alcohol. Clin. Exp. Res. 1998; 22: S225 30.
- 33, , , Ethanol-induced mobilization of calcium by activation of phosphoinositide-specific phospholipase C in intact hepatocytes. J. Biol. Chem. 1987; 262: 682 91.
- 34, , , Redox control of gene expression by eukaryotic transcription factors NF-κB, AP-1 and SRF/TCF. In: Pasquier C, ed. Oxidative Stress, Cell Activation and Viral Infection>. Basel: Birhauser-Verlag, 1994; 217 35.
- 35, , et al. The HIV-1 gp120 envelope protein has the intrinsic capacity to stimulate monokine production. J. Immunol. 1991; 147: 2892 901.
- 36, , et al. The production of β-chemokines induced by HIV-2 envelope glycoprotein. AIDS 1995; 11: 1063 4.
- 37, , , , MIP-1 nuclear protein (MNP), a novel transcription factor expressed in hematopoietic cells that is crucial for transcription of human MIP-1 gene. Mol. Cell. Biol. 1995; 15: 3110 18.
- 38, , , , The effect of LPS on expression of the early competence gene JE and gene KC in murine peritoneal macrophages. J. Immunol. 1987; 138: 3891 6.
- 39, , Ethanol-related liver injury in the rat: A model of steatosis, inflammation and pericentral necrosis. J. Hepatol. 1995; 23: 591 600.
- 40& Cross-tolerance between acute alcohol intoxication and endotoxemia. Alcohol. Clin. Exp. Res. 1996; 20: 1395 400.Direct Link:
- 41& Acute endotoxin tolerance downregulates superoxide anion release by the perfused liver and isolated hepatic non-parenchymal cell. Hepatology 1995; 21: 855 62.
- 42& Cytokine gene expression by Kupffer cells in experimental alcoholic liver disease. Hepatology 1995; 21: 1304 9.
- 43& The role of Kupffer cells in liver injury. In: Wisse E, Knook DL, Balabaud C, eds. Cells of the Hepatic Sinusoids, Vol. 6. Leiden: Kupffer Cell Foundation, 1994; 224 50.
- 44Adenovirus-mediated expression of CINC in rat liver induces neutrophilic hepatotoxicity. Hepatology 1997; 25: 624 30.Direct Link:
- 45, , , Altered T-lymphocyte responsiveness to polyclonal cell activators is responsible for liver cell necrosis in alcohol-fed rats. Alcohol. Clin. Exp. Res. 1998; 22: 723 9.Direct Link:
- 46Coreceptors. Implications for HIV-1 pathogenesis and therapy. Science 1997; 276: 51 2.
- 47, , , , , Increased replication of T-cell-tropic HIV strains and CXC-chemokine receptor-4 induction in T cells treated with macrophage inflammatory protein-1 alpha, MIP-1 beta and RANTES beta-chemokines. AIDS 1998; 12: 183 90.
- 48, , , , Genetically divergent strains of SIV use CCR5 coreceptor for entry. J. Virol. 1997; 71: 2705 14.
- 49, , , , , Differential expression of monocyte chemotactic protein-1 (MCP-1) in transforming rat hepatic stellate cells. J. Hepatol. 1999; 30: 88 94.
- 50, , , , , T cell stimulus-induced crosstalk between lymphocytes and liver macrophages results in augmented cytokine release. Exp. Cell. Res. 1996; 229: 137 46.

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