Prostatic stromal sarcoma: Case report and review of the literature
Article first published online: 17 JUN 2003
Volume 53, Issue 6, pages 407–411, June 2003
How to Cite
Osaki, M., Osaki, M., Takahashi, C., Miyagawa, T., Adachi, H. and Ito, H. (2003), Prostatic stromal sarcoma: Case report and review of the literature. Pathology International, 53: 407–411. doi: 10.1046/j.1440-1827.2003.01489.x
- Issue published online: 17 JUN 2003
- Article first published online: 17 JUN 2003
- Received 29 October 2002. Accepted for publication 8 February 2003.
- stromal sarcoma
We report a case of a 65-year-old man with rare prostatic stromal sarcoma in which suprapubital radical prostatectomy was performed, but neither chemotherapy nor radiation therapy were administered before or after the operation. The well-circumscribed tumor, measuring 5 cm in diameter, showed a homogeneous white grayish cut surface with a hard consistency. Histopathologically, the tumor consisted mainly of medium-sized rounded cells with a sarcomatous and epithelioid appearance intermingled with collagen fiber. Hyalinized foci were also noted in the tumor. Immunohistochemistry revealed that the tumor cells were diffusely positive for vimentin and focally positive for progesterone receptor and CD34, but not for EMA, cytokeratin or estrogen receptor. No recurrence or distant metastasis of the tumor has occurred in 8 years of follow up. The tumor was diagnosed as prostatic stromal sarcoma (PSS) showing epithelioid differentiation and of a progesterone-dependent nature. Possible favorable nature of the PSS might be expected after complete resection.