Pneumococcal keratitis: a clinical profile
Article first published online: 12 FEB 2003
Clinical & Experimental Ophthalmology
Volume 31, Issue 1, pages 44–47, February 2003
How to Cite
Parmar, P., Salman, A., Kalavathy, C. M., Jesudasan, C. N. and Thomas, P. A. (2003), Pneumococcal keratitis: a clinical profile. Clinical & Experimental Ophthalmology, 31: 44–47. doi: 10.1046/j.1442-9071.2003.00598.x
- Issue published online: 12 FEB 2003
- Article first published online: 12 FEB 2003
- chronic dacryocystitis;
- infectious keratitis;
- Streptococcus pneumoniae
Aim: To study the clinical features of pneumococcal keratitis and response to ciprofloxacin therapy.
Methods: A retrospective analysis was undertaken of 58 patients with culture-proven pneumococcal keratitis seen over a period of 2 years.
Results: Pneumococcal keratitis accounted for 33.3% of bacterial keratitis. Most cases presented with non-severe keratitis (77.5%). Co-existing sac pathology was more frequent in pneumococcal ulcers as compared to non-pneumococcal bacterial ulcers (50%vs 9%, P < 0.001). Characteristic clinical features enabling an accurate clinical diagnosis were found in 27.5% and lanceolate diplococci on Gram's stain were identified in 76% of cases. In vitro testing showed a high susceptibility to cephazolin and ciprofloxacin. All patients received ciprofloxacin as first-line therapy. Eighty per cent responded well with complete healing of the ulcer. A second drug was required in 8.5%.
Conclusion: Ciprofloxacin therapy can be effective in the treatment of pneumococcal keratitis.