Does quazepam influence sleep and daytime activity in healthy adults?
Version of Record online: 10 JUN 2003
Sleep and Biological Rhythms
Volume 1, Issue 2, pages 171–172, June 2003
How to Cite
KUSUNOKI, K., KITAJIMA, T. and OZAKI, N. (2003), Does quazepam influence sleep and daytime activity in healthy adults?. Sleep and Biological Rhythms, 1: 171–172. doi: 10.1046/j.1446-9235.2003.00036.x
- Issue online: 10 JUN 2003
- Version of Record online: 10 JUN 2003
- Accepted for publication 14 January 2003.
- daytime activity;
A pilot study using actigraph was conducted to assess the effects of a 1-week repeated administration of 15 mg of quazepam on the sleep and daytime activity of six healthy adults. The nocturnal sleep time gradually increased during quazepam administration, and a significant difference from the baseline was noted on the seventh day of administration. There was no significant difference in the daytime activity before and after the administration. Quazepam and its active metabolites appear to have acted on the level not affecting the daytime activity but prolonging the nocturnal sleep time through their interactions.