Extrapyramidal side-effects from droperidol mixed with morphine for patient-controlled analgesia in two children

  1. W. Habre,
  2. D. Wilson,
  3. C.M. Johnson

Article first published online: 4 JAN 2002

DOI: 10.1046/j.1460-9592.1999.00347.x

Issue

Pediatric Anesthesia

Pediatric Anesthesia

Volume 9, Issue 4, pages 362–364, July 1999

Additional Information

How to Cite

Habre, W., Wilson, D. and Johnson, C. (1999), Extrapyramidal side-effects from droperidol mixed with morphine for patient-controlled analgesia in two children. Pediatric Anesthesia, 9: 362–364. doi: 10.1046/j.1460-9592.1999.00347.x

Author Information

  1. Princess Margaret Hospital for Children, Perth, Western Australia

* W.Habre Division of Paediatric Anaesthesia, Geneva Children's Hospital, 6, rue Willy Donze, 1205 Geneva, Switzerland.

Publication History

  1. Issue published online: 4 JAN 2002
  2. Article first published online: 4 JAN 2002

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Keywords:

  • patient-controlled analgesia;
  • droperidol;
  • dystonic reactions

Summary

We report two cases of extrapyramidal reactions occurring in children following the use of droperidol in combination with morphine for patient-controlled analgesia (PCA). Symptoms appeared 38 and 27 h, respectively, after commencement and after a total dose of 0.14 mg·kg−1 and 0.17 mg·kg−1, respectively. Although effective and safe in adult patients, we recommend caution with the use of droperidol-morphine mixtures for PCA in paediatric patients.

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