Extension of Generator Longevity by Use of High Impedance Ventricular Leads
Article first published online: 22 JUL 2003
© Futura Publishing Company, Inc. 2001
Pacing and Clinical Electrophysiology
Volume 24, Issue 2, pages 206–211, February 2001
How to Cite
SCHERER, M., EZZIDDIN, K., KLESIUS, A., SKUPIN, M., HELMS, S., MORITZ, A. and OLBRICH, H.-G. (2001), Extension of Generator Longevity by Use of High Impedance Ventricular Leads. Pacing and Clinical Electrophysiology, 24: 206–211. doi: 10.1046/j.1460-9592.2001.00206.x
- Issue published online: 22 JUL 2003
- Article first published online: 22 JUL 2003
- Received January 18, 2000; revised June 9, 2000; accepted July 19, 2000.
- Cited By
- high impedance;
- current drain;
- pacemaker longevity;
- steroid-eluting electrode
SCHERER, M., et al.: Extension of Generator Longevity by Use of High Impedance Ventricular Leads. The resistance of a pacing lead negatively correlates to current consumption. A prospective, randomized trial was conducted to evaluate the effect of a high impedance ventricular lead (CapSure Z) on generator longevity compared to a conventional lead (CapSure SP) eighty-nine patients were included in the study (51 male, 37 female, age 70.0 ± 10.3 years). Forty-six patients received a CapSure SP lead (5024 bipolar), and 43 patients received a CapSure Z lead (5034 bipolar) in a randomized fashion. Follow-up data collected at 5 days, 3, 6, and 12 months postimplant included: lead impedance, pacing and sensing thresholds, impulse energy, and estimated time to replacement. All parameters were collected via pacemaker telemetry; the time to replacement was calculated automatically by a programmed algorithm of the pacemaker. There was no difference in the performance of the atrial lead when a dual chamber device was indicated. The CapSure Z leads displayed statistically significant higher impedance values than the CapSure SP lead in all follow-up periods. There was no significant difference in lead related complications. No significant differences were observed between pacing and sensing thresholds in both groups. The CapSure Z leads provided a significant reduction in current drain, resulting in a reduction of mean energy consumption at the 12-month follow-up from 10.4 ± 5.0 μJ in the CapSure SP group to 6.6 ± 1.4 μJ in the CapSure Z group (median from 9.9 μJ to 6.9 μJ, respectively), providing an estimated increase in mean longevity of more than 1 year from 81.1 ± 23.5 months in the CapSure SP group to 94.5 ± 13.4 months in the CapSure Z group (median: 76.5 months to 95.0 months, respectively). The use of a high resistance lead for ventricular pacing appears to result in a clinically relevant extension of generator longevity.