Neuropsychological functioning in older people with Type 2 diabetes: the effect of controlling for confounding factors
Article first published online: 9 APR 2002
Volume 19, Issue 4, pages 311–316, April 2002
How to Cite
Asimakopoulou, K. G., Hampson, S. E. and Morrish, N. J. (2002), Neuropsychological functioning in older people with Type 2 diabetes: the effect of controlling for confounding factors. Diabetic Medicine, 19: 311–316. doi: 10.1046/j.1464-5491.2002.00680.x
- Issue published online: 9 APR 2002
- Article first published online: 9 APR 2002
- Accepted 9 October 2001
- neuropsychological function;
- Type 2 diabetes;
- older patients
Aims and methods Neuropsychological functioning was examined in a group of 33 older (mean age 62.40 ± 9.62 years) people with Type 2 diabetes (Group 1) and 33 non-diabetic participants matched with Group 1 on age, sex, premorbid intelligence and presence of hypertension and cardio/cerebrovascular conditions (Group 2).
Results Data statistically corrected for confounding factors obtained from the diabetic group were compared with the matched control group. The results suggested small cognitive deficits in diabetic people’s verbal memory and mental flexibility (Logical Memory A and SS7). No differences were seen between the two samples in simple and complex visuomotor attention, sustained complex visual attention, attention efficiency, mental double tracking, implicit memory, and self-reported memory problems.
Conclusions These findings indicate minimal cognitive impairment in relatively uncomplicated Type 2 diabetes and demonstrate the importance of control and matching for confounding factors.