PENTA guidelines for the use of antiretroviral therapy in paediatric HIV infection

Authors


  • *

    Members of the PENTA Steering Committee are listed in the Appendix.

Dr Mike Sharland, Paediatric Infectious Diseases Unit, St George's Hospital, Blackshaw Road, London SW17 0QT, UK. e-mail: mike.sharland@stgeorges.nhs.uk

Abstract

Objective

To produce European Guidelines for the use of antiretroviral therapy (ART) in HIV-infected children.

Design

Systematic literature review using Medline, the major antiretroviral conference reports, and IDSA recommendations on guideline production.

Setting

Pediatric European Network for Treatment of AIDS (PENTA) Steering Committee.

Outcome measure

Guidelines have been produced for the use of antiretroviral therapy in HIV-infected children in Europe. Recommendations on when to start ART and which ART to start, with dosages and a summary of the relevant literature, have been produced.

Conclusions

These guidelines are aimed at assisting paediatricians in Europe with ART prescribing, and provide a more cautious approach to starting therapy than current paediatric USA guidelines.

Ancillary