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An ischemic stroke during intravenous recombinant tissue plasminogen activator infusion for evolving myocardial infarction
Article first published online: 21 DEC 2001
DOI: 10.1046/j.1468-1331.2001.00216.x
1468-1331/asset/cover.gif?v=1&s=02086c94ae38501b239f31e52894de795d835902 "European Journal of Neurology")
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How to Cite
Chang, G. Y. (2001), An ischemic stroke during intravenous recombinant tissue plasminogen activator infusion for evolving myocardial infarction. European Journal of Neurology, 8: 267–268. doi: 10.1046/j.1468-1331.2001.00216.x
Publication History
- Issue published online: 21 DEC 2001
- Article first published online: 21 DEC 2001
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Keywords:
- ischemic stroke;
- myocardial infarction;
- tissue plasminogen activator
A 56-year-old man without a previous history of stroke received intravenous recombinant tissue plasminogen activator (tPA) for an evolving myocardial infarction. During the infusion, the patient developed aphasia and right hemiparesis. The CT and MRI confirmed an ischemic stroke without evidence of hemorrhage. Although the cerebral hemorrhage after tPA infusion is relatively more common, in rare cases, tPA infusion may result in fragmentation of a cardiac thrombus resulting in an ischemic cerebral stroke.