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Keywords:

  • Cyclic vomiting syndrome;
  • abdominal migraine;
  • migraine genes;
  • CACNA1A

A family is described in which four members suffer from cycling vomiting syndrome (CVS), without additional symptoms. So far, only a few CVS families have been described in literature, and most patients belonging to these families had other symptoms in addition to CVS. We conclude that ‘pure’ CVS may also be a hereditary disorder. Its relation to migraine will be discussed.