Fetal liver volume measurement by three-dimensional ultrasonography: a preliminary study
Article first published online: 24 DEC 2002
Copyright © 1998 ISUOG.
Ultrasound in Obstetrics & Gynecology
Volume 12, Issue 2, pages 93–96, August 1998
How to Cite
Laudy, J. A. M., Janssen, M. M. M., Struyk, P. C., Stijnen, T., Wallenburg, H. C. S. and Wladimiroff, J. W. (1998), Fetal liver volume measurement by three-dimensional ultrasonography: a preliminary study. Ultrasound Obstet Gynecol, 12: 93–96. doi: 10.1046/j.1469-0705.1998.12020093.x
- Issue published online: 24 DEC 2002
- Article first published online: 24 DEC 2002
- Manuscript Accepted: 27 MAY 1998
- Manuscript Revised: 29 APR 1998
- Manuscript Received: 18 SEP 1997
- Cited By
- Three-Dimensional Ultrasonography;
- Liver Volume
To establish the application of three-dimensional ultrasonography in measuring fetal liver volume during the second half of normal pregnancy.
A prospective cross-sectional study of normal fetal liver volume at 19–39 weeks of gestation (median 29 weeks).
Thirty-four non-smoking women with a singleton pregnancy resulting in the delivery of a healthy infant with a birth weight between the 5th and 95th centiles according to the Kloosterman tables adjusted for maternal parity and fetal sex.
For fetal liver volume measurements, a simultaneous recording of a frontal section of the liver immediately anterior to the stomach and a sagittal section of the liver were obtained using a standard Combison 530 ultrasound machine with a 5-MHz annular array transducer for volume scanning.
Technically acceptable fetal liver volume measurements were obtained in 25 of 34 participating women. Mean fetal liver volume data (P50) ranged between 8 ml at 20 weeks' gestation and 116 ml at 38 weeks' gestation. A statistically significant increase in normal fetal liver volume was found with advancing gestational age (p < 0.0001) and with increasing estimated fetal weight (p < 0.0001).
Three-dimensional ultrasound allows measurement of fetal liver volume, and this demonstrated an approximately 14-fold increase during the second half of pregnancy. It is speculated that three-dimensional fetal liver volume measurement may identify the fetus at risk of growth restriction. Copyright © 1998 International Society of Ultrasound in Obstetrics and Gynecology