The detection of spina bifida before 10 gestational weeks using two- and three-dimensional ultrasound

Authors

  • H.-G. K. Blaas MD PhD,

    Corresponding author
    1. National Center for Fetal Medicine, Department of Obstetrics and Gynecology, Norwegian University of Science and Technology, Trondheim University Hospital, Trondheim, Norway
    • National Center for Fetal Medicine, Department of Obstetrics and Gynecology, Norwegian University of Science and Technology, Trondheim University Hospital, N-7006 Trondheim, Norway
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  • S. H. Eik-Nes,

    1. National Center for Fetal Medicine, Department of Obstetrics and Gynecology, Norwegian University of Science and Technology, Trondheim University Hospital, Trondheim, Norway
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  • C. V. Isaksen

    1. Institute of Morphology and Department of Pathology, Norwegian University of Science and Technology, Trondheim University Hospital, Trondheim, Norway
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Abstract

We present three cases of spina bifida during the embryonic period detected by ultrasound before 10 weeks' gestational age. The last-menstrual-period-based ages ranged from 9 weeks 1 day to 9 weeks 4 days and the crown rump lengths ranged from 22 mm to 28 mm. The cases were identified prospectively in a program of targeted ultrasound examination of high-risk pregnancies, using a 7.5 MHz annular array transvaginal transducer. The use of 3D ultrasound made additional diagnostic ultrasound tomograms possible, but was not necessary for the definite diagnosis. The scalloping of the frontal bones and the Arnold Chiari malformation did not occur before 12 weeks. Copyright © 2000 International Society of Ultrasound in Obstetrics and Gynecology

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