Sonographic appearance of first trimester complete hydatidiform moles

Authors

  • C. B. Benson MD,

    Corresponding author
    1. Department of Radiology, New England Trophoblastic Disease Center, Division of Gynecologic Oncology, Harvard Medical School and Brigham and Women's Hospital and Dana Farber Cancer Institute, Boston, MA, USA
    • Department of Radiology, Brigham and Women's Hospital, 75 Francis St., Boston, MA 02115, USA
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  • D. R. Genest,

    1. Department of Pathology, New England Trophoblastic Disease Center, Division of Gynecologic Oncology, Harvard Medical School and Brigham and Women's Hospital and Dana Farber Cancer Institute, Boston, MA, USA
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  • M. R. Bernstein,

    1. Department of Obstetrics, Gynecology, and Reproductive Biology, New England Trophoblastic Disease Center, Division of Gynecologic Oncology, Harvard Medical School and Brigham and Women's Hospital and Dana Farber Cancer Institute, Boston, MA, USA
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  • V. Soto-Wright,

    1. Department of Obstetrics, Gynecology, and Reproductive Biology, New England Trophoblastic Disease Center, Division of Gynecologic Oncology, Harvard Medical School and Brigham and Women's Hospital and Dana Farber Cancer Institute, Boston, MA, USA
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  • D. P. Goldstein,

    1. Department of Obstetrics, Gynecology, and Reproductive Biology, New England Trophoblastic Disease Center, Division of Gynecologic Oncology, Harvard Medical School and Brigham and Women's Hospital and Dana Farber Cancer Institute, Boston, MA, USA
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  • R. S. Berkowitz

    1. Department of Obstetrics, Gynecology, and Reproductive Biology, New England Trophoblastic Disease Center, Division of Gynecologic Oncology, Harvard Medical School and Brigham and Women's Hospital and Dana Farber Cancer Institute, Boston, MA, USA
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Abstract

Objective

Complete hydatidiform moles are now being diagnosed earlier in gestation, thus the clinical presentation and pathologic findings of complete molar pregnancy have changed. We studied the sonographic appearance of first trimester moles and the ability of ultrasound to detect them.

Methods

We reviewed the sonographic interpretation and sonograms, when available, from all patients with first trimester complete moles diagnosed at our institution from January 1988 to March 1996.

Results

Of the 24 patients in our study, the mean gestational age at time of the sonogram was 8.7 ± 2.0 weeks (mean ± SD) with a range of 5.7–12.3 weeks. The initial sonographic interpretation was a complete mole in 17 (71%) cases, partial mole versus failed pregnancy in two (8%), and failed pregnancy in five (21%) cases. Of the 22 patients with sonograms available for review, interpretation on review of the images was a complete mole in 18 (82%) cases, partial mole versus failed pregnancy in one (5%), and failed pregnancy in three (14%) cases. The typical sonographic appearance of a first trimester complete mole was a complex, echogenic, intra-uterine mass containing many small cystic spaces.

Conclusion

The majority of first trimester complete moles demonstrate a typical ultrasound appearance such that the diagnosis can be made with ultrasound in most cases. Copyright © 2000 International Society of Ultrasound in Obstetrics and Gynecology

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