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Acknowledgements

We thank Dr. I. A. Romero for the critical reading of the manuscript and I. Bouchaert for technical support with the confocal microscopy. This study was supported by the Programa Praxis XXI of the Fundaçao para a Ciência e Tecnologia and Programa Gulbenkian de Doutoramento em Biologia e Medicina, the Centre National de la Recherche Scientifique, the Institut National de la Recherche Médicale, the Association pour le Développement de la Recherche sur le Cancer, the Ligue Nationale Française contre le Cancer, the Université de Paris, and the Ministère de la Recherche et de L'Enseignement Supérieur.

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