This study was supported by NIH grants AG12282 and CA69381 to D.E.B, and by the Glendon Foundation (Catherine Dorn, trustee). The work of G.S.S. was supported by NIH HL513999. H.M.E. is a NIH Senior Research Fellow (NS10050). The work of M.R.H. and L.P. is supported by the Canadian Networks of Centres of Excellence (NCE-Genetics) and MRC (Canada) operating grants. M.R.H. is an established investigator of the B.C. Children's Hospital. C.L.W. and A.S.H. are Alberta Heritage Foundation for Medical Research postdoctoral fellows. We thank E. Wilson for providing a wild-type androgen receptor cDNA.

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