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Acknowledgements

This study was supported by FNSRS grant 3100-052242.97 (J.G.), Bern, Switzerland, and by DGICYT grant PB94-0002-Mod C (J.A.G.-S.), Madrid, Spain. A.O. was supported by a fellowship from the Basque Government, Vitoria/Gasteiz, Spain. We thank Dr. Ch. Staub of the Unité de Toxicologie, Université de Genève, who supplied the toxicological data of the HUG series and Dr. A. Moreno, Servicio de Psiquiatría, Hospital “Son Dureta,” who supplied the clinical data of the UIB series. J.A.G.-S. is a member of the Institut d'Estudis Catalans.

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