The authors gratefully acknowledge Marcia Lloyd, Walid Moghrabi, Roxana Radu, and Alice Van Dyke for their outstanding technical assistance, Bobby Korn for his help with site-directed mutagenesis, Jane Johnson for her help with oocyte injection, and Sassan Azarian for his insightful comments on the manuscript. This work was supported by grants EY08043, EY00444, and EY00331 from the National Eye Institute and a grant from the Foundation Fighting Blindness. D.B. is the Dolly Green Professor of Ophthalmology at UCLA and a Research to Prevent Blindness Senior Scientific Investigator.

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