The authors wish to thank Dr. M. Del Bigio for helpful comments. Research was supported by grants from the Medical Research Council of Canada. F.E.P. is a Scholar of the Medical Research Council of Canada. C.E.C. is a Terry Fox Cancer Research Scientist of the National Cancer Institute of Canada. J.D.Y. is a Heritage Medical Scientist of the Alberta Heritage Foundation for Medical Research. C.M.A. is a trainee of the Heart and Stroke Foundation of Canada.

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