• 1
    Alexinsky T., Przbyslawski J., Mileusnic R., Rose S.P.R., Sara S.J. (1997) Antibody to day-old chick brain glycoprotein produces amnesia in adult rats. Neurobiol. Learn. Mem. 67 1420.DOI: 10.1006/nlme.1996.3734
  • 2
    Andersson A.M., Olsen M., Zhernosekov D., Gaardsvoll H., Krog L., Linnemann D., Bock E. (1993) Age-related changes in expression of the neural cell adhesion molecule in skeletal muscle: a comparative study of newborn, adult and aged rats. Biochem. J. 290 641648.
  • 3
    Arami S., Jucker M., Schachner M., Welzl H. (1996) The effect of continuous intraventricular infusion of L1 and NCAM antibodies on spatial learning in rats. Behav. Brain. Res. 81 8187.
  • 4
    Atkins A.R., Osborne M.J., Lashuel H.A., Edelman G.M., Wright P.E., Cunningham B.A., Dyson J.H. (1999) Association between the first two immunoglobulin-like domains of the neural cell adhesion molecule N-CAM. FEBS Lett. 451 162168.
  • 5
    Bailey C.H., Chen M., Keller F., Kandel E.R. (1992) Serotonin-mediated endocytosis of apCAM: an early step of learning-related synaptic growth in Aplysia. Science 256 645649.
  • 6
    Beggs H.E., Baragona S.C., Hemperly J.J., Maness P.F. (1997) NCAM140 interacts with the focal adhesion kinase p125fak and the SRC-related tyrosine kinase p59fyn. J. Biol. Chem. 272 83108319.
  • 7
    Doubell T.P. & Stewart M.G. (1993) Short-term changes in the numerical density of synapses in the intermediate and medial hyperstriatum ventrale following one-trial passive avoidance training in the chick. J. Neurosci. 13 22302236.
  • 8
    Doyle E., Nolan P.M., Bell R., Regan C.M. (1992a) Intraventricular infusions of anti-neural cell adhesion molecules in a discrete posttraining period impair consolidation of a passive avoidance response in the rat. J. Neurochem. 59 15701573.
  • 9
    Doyle E., Nolan P.M., Bell R., Regan C.M. (1992b) Neurodevelopmental events underlying information acquisition and storage. Network 3 8994.
  • 10
    Fox G.B., O'Connell A.W., Murphy K.J., Regan C.M. (1995) Memory consolidation induces a transient and time-dependent increase in the frequency of neural cell adhesion molecule polysialylated cells in the adult rat hippocampus. J. Neurochem. 65 27962799.
  • 11
    Geinisman G., DeToledo-Morrell L., Morrell F. (1991) Induction of long-term potentiation is associated with an increase in the number of axospinous synapses with segmented postsynaptic densities. Brain Res. 566 7788.
  • 12
    Greenough W.T. & Bailey C.H. (1988) The anatomy of a memory: convergence of results across a diversity of tests. Trends Neurosci. 11 142147.
  • 13
    Hegde A.N., Inokuchi K., Pei W., Casadio A., Ghirardi M., Chain D., Martin K.C., Kandel E.R., Schwartz J.H. (1997) Ubiquitin C-terminal hydrolase is an intermediate-early gene for long-term facilitation in Aplysia. Cell 89 115126.
  • 14
    Hoffman K.B., Larson J., Bahr B.A., Lynch G. (1998) Activation of NMDA receptors stimulates extracellular proteolysis of cell adhesion molecules in the hippocampus. Brain Res. 811 152155.
  • 15
    Horstkorte R., Schachner M., Magyar J.P., Vorherr T., Schmitz B. (1993) The fourth immunoglobulin-like domain of NCAM contains a carbohydrate recognition domain for oligomannosidic glycans implicated in association with L1 and neurite outgrowth. J. Cell Biol. 121 14091421.
  • 16
    Hunter A. & Stewart M.G. (1993) Long-term increases in the numerical density of synapses in the chick lobus parolfactorius after passive avoidance training. Brain Res. 605 251255.
  • 17
    Jensen P.H., Soroka V., Thomsen N.K., Ralets I., Berezin V., Bock E., Poulsen F.M. (1999) Structure and interactions of NCAM modules 1 and 2—basic elements in neural cell adhesion. Nat. Struct. Biol. 6 486493.
  • 18
    Kadmon G., Kowitz A., Altevogt P., Schachner M. (1990) Functional co-operation between the neuronal adhesion molecules L1 and N-CAM is carbohydrate dependent. J. Cell Biol. 110 209218.
  • 19
    Kiselyov V.V., Berezin V., Maar T.E., Soroka V., Edvardsen K., Schousboe A., Bock E. (1997) The first Ig-like NCAM domain is involved in double reciprocal interaction with the second Ig-like NCAM domain and in heparin binding. J. Biol. Chem. 272 1012510134.
  • 20
    Lowry O.H., Rosebrough N.J., Farr A.L., Randall R.J. (1951) Protein measurement with the Folin reagent. J. Biol. Chem. 193 265275.
  • 21
    Lüthl A., Laurent J.P., Figurov A., Muller D., Schachner M. (1994) Hippocampal long-term potentiation and neural cell adhesion molecules L1 and NCAM. Nature 372 777779.
  • 22
    Lynch G. (1998) Memory and the brain: unexpected chemistries and a new pharmacology. Neurobiol. Learn. Mem. 70 82100.
  • 23
    Mayford M., Barzilai A., Keller F., Schacher S., Kandel E.R. (1992) Modulation of an NCAM-related adhesion molecule with long-term synaptic plasticity in Aplysia. Science 256 638644.
  • 24
    Nolan P.M., Bell R., Regan C.M. (1987) Acquisition of a brief behavioural experience in the presence of neuron-specific and D2-CAM/N-CAM-specific antisera. Neurochem. Res. 12 619624.
  • 25
    O'Malley A., O'Connell C., Regan C.M. (1998) Ultrastructural analysis reveals avoidance conditioning to induce a transient increase in hippocampal dentate spine density in the 6h post-training period of consolidation. Neuroscience 87 607613.
  • 26
    Park T.V., Lucka L., Reutter W., Horstkorte R. (1997) Turnover studies of the neural cell adhesion molecule NCAM: degradation of NCAM in PC12 cells depends on the presence of NGF. Biochem. Biophys. Res. Commun. 234 686689.
  • 27
    Rønn L.C.B., Bock E., Linneman D., Jahnsen H. (1995) NCAM-antibodies modulate induction of long-term potentiation in rat hippocampal CA1. Brain Res. 677 145151.
  • 28
    Rønn L.C.B., Olsen M., Østergaard S., Kiselyov V., Berezin V., Soroka V., Saffell J., Doherty P., Bock E., Holm A. (1999) Stimulation of neurite outgrowth by a synthetic NCAM ligand identified by means of combinatorial peptide libraries. Nat. Biotechnol. 17 10001005.
  • 29
    Rose S.P.R. (1996) Cell adhesion molecules and the transition from short- to long-term memory. J. Physiol. (Lond.) 90 387391.
  • 30
    Roullet P., Mileusnic R., Rose S.P.R., Sara S.J. (1997) Neural cell adhesion molecules play a role in rat memory formation in appetitive as well as aversive tasks. Neuroreport 8 19071911.
  • 31
    Saffell J.L., Williams E.J., Mason I.J., Walsh F.S., Doherty P. (1997) Expression of a dominant negative FGF receptor inhibits axonal growth and FGF receptor phosphorylation by CAMs. Neuron 18 231242.
  • 32
    Schmid R.S., Graff R.D., Schaller M.D., Chen S., Schachner M., Hemperly J.J., Maness P.F. (1999) NCAM stimulates the Ras-MAPK pathway and CREB phosphorylation in neuronal cells. J. Neurobiol. 38 45424558.
  • 33
    Scholey A.B., Rose S.P.R., Zamani M.R., Bock E., Schachner M. (1993) A role for neural cell adhesion molecule in a late-consolidating phase of glycoprotein synthesis 6 hours following passive avoidance training of the young chick. Neuroscience 55 499509.
  • 34
    Scholey A.B., Mileusnic R., Schachner M., Rose S.P.R. (1995) A role for a chicken homolog of the neural cell adhesion molecule L1 in consolidation of memory for a passive avoidance task in the chick. Learn. Mem. 2 1725.
  • 35
    Schuster T., Krug M., Hassan H., Schachner M. (1998) Increase in proportion of hippocampal spine synapses expressing neural cell adhesion molecule NCAM 180 following long-term potentiation. J. Neurobiol. 37 359372.DOI: 10.1002/(SICI)1097-4695(19981115)37:3<359::AID-NEU2>3.0.CO;2-4
  • 36
    Skibo G.C., Davies H.A., Rusakov D.A., Stewart M.G., Schachner M. (1998) Increased immunogold labelling of neural cell adhesion molecule isoforms in synaptic active zones of the chick striatum 5-6 hours after one-trial passive avoidance training. Neuroscience 82 15.
  • 37
    Stewart M.G. & Rusakov D.A. (1995) Morphological changes associated with stages of memory formation in the chick following passive avoidance training. Behav. Brain Res. 66 2128.
  • 38
    Thomsen N.K., Soroka V., Jensen P.H., Berezin V., Kiselyov V.V., Bock E. (1996) The three-dimensional structure of the first domain of neural cell adhesion molecule. Nat. Struct. Biol. 3 581585.
  • 39
    Tiunova A., Anokhin K.V., Rose S.P.R. (1998) Three time windows for amnestic effect of antibodies to cell adhesion molecule L1 in chicks. Neuroreport 9 16451648.
  • 40
    Toni N., Buchs P., Nikonenko I., Bron C.R., Muller D. (1999) LTP promotes formation of multiple spine synapses between a single axon terminal and a dendrite. Nature 402 421425.
  • 41
    Vanderklish P., Saido T.C., Gall C., Arai A., Lynch G. (1995) Proteolysis of spectrin by calpain accompanies theta-burst stimulation in cultured hippocampal slices. Brain Res. Mol. Brain Res. 32 2535.
  • 42
    Williams E.J., Furness J., Walsh F.S., Doherty P. (1994) Activation of the FGF receptor underlies neurite outgrowth stimulated by L1, NCAM, and N-cadherin. Neuron 13 583594.