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Acknowledgements

We are grateful to Prof. E. N. Benveniste for providing cDNA for a partial TNF-α. We thank Ms. Yasuko Takeuchi, Ms. Mayumi Sora, and Mr. Tomohisa Suzuki for their technical assistance, Dr. Faiz Kermani for his helpful comments, and the Research Center for Molecular Medicine, Hiroshima University School of Medicine, for the use of its facilities. This study was supported by Grant-in-Aid 11670089 from the Ministry of Education, Science and Culture, Japan and partly supported by the Promotion of Fundamental Studies in Health Science of the Organization for Pharmaceutical Safety and Research.

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