The helpful discussions with Dr. S. Pal and D. Limbrick, M.S., were greatly appreciated. In addition, the authors would like to thank Dr. J. J. Feher for his invaluable expertise with microsomal Mg2+/Ca2+ ATPase. This work was supported by NINDS awards RO1 NS23350 and PO1 NS25630 to Robert J. DeLorenzo and NSO 7288-13 to J. Travis Parsons. The work was also supported by the Sophie and Nathan Gumenick Neuroscience Research Fund and the Milton L. Markel Alzheimer and Neuroscience Research Fund.

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