We thank Drs. Todd Morgan and Edith Gralla for helpful comments. We thank Pat Wals and Iman Mohtashemi for the preparation of clusterin. This work was supported by NIH grant AG13499 to C.E.F. and by a John Douglas French Alzheimer's Foundation grant to V.D.L. We thank Mr. John Martin and Mr. George Fenimore for their generous donations.

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