This study was supported by grant MT-14466 from the Medical Research Council of Canada (MRC), which is part of an MRC group grant (MGC 11474). The authors wish to thank Dr. Frédéric Checler (Université de Nice—Sophia Antipolis, Valbonne, France) for providing the monospecific antibody FCA18. We acknowledge the expert technical assistance of Mrs. Ainta M. Mamarbassi and Louise Wickham for PCR and cloning work, Jadwiga Marcinkiewicz for northern blots and in situ hybridization work, and Mr. Christian Charbonneau for assistance in computer imaging. Special thanks are to Mrs. Danielle Cécyre, Coordinator, from the Brain Bank (Douglas Hospital Research Centre, Verdun, Quebec, Canada) for providing us with human tissues. We also wish to thank Dr. Michel Chrétien from the Loeb Health Research Institute (Ottawa, Ontario, Canada) for encouragement in performing this research, Drs. Giuseppe Biagini (University of Modena, Modena, Italy) and Annik Prat for review of the manuscript and scientific discussion, and Mrs. Sylvie Emond for secretarial assistance.

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