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Acknowledgements

This work was supported by grant NS30318 from the National Institutes of Health, grant AICR 97-B128 from the Department of Veterans Affairs Medical Service Merit Review, the Wellcome Trust, and fellowships from the National Cancer Institute Oncology Research Faculty Development Program, Magee—Womens Research Institute, the Leukemia Research Foundation, and the International Neurological Science Fellowship Program (F05 NS 10669) administered by the National Institute of Neurological Disorders and Stroke, National Institutes of Health, in collaboration with the Unit of Neuroscience, Division of Mental Health and Prevention of Substance Abuse, World Health Organization.

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