This work was supported by the Deutsche Forschungsgemeinschaft (SFB 539),the Bundesministerium für Bildung und Forschung,and the Fonds der Chemischen Industrie. We thank Dr. Peter Seeburg(Max-Planck-Institut für Medizinische Forschung,Heidelberg, Germany) for providing NMDA receptor subunit expression vectorsand Dr. Hans-Georg Breitinger for a critical reading of the manuscript.

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