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  • 1
    Bai G. & Kusiak J.W. (1997) Nerve growth factor up-regulates the N-methyl-D-aspartate receptor subunit 1 promoter in PC12 cells. J. Biol. Chem. 28 59365942.
  • 2
    Barbacid M. (1994) The Trk family of neurotrophin receptors. J. Neurobiol. 25 13861403.
  • 3
    Baxter R.M., Cohen P., Obermeier A., Ullrich A., Downes C.P., Doza Y.N. (1995) Phosphotyrosine residues in the nerve-growth-factor receptor (TrkA): their role in the activation of inositolphospholipid metabolism and protein kinase cascades in pheochromocytoma (PC12) cells. Eur. J. Biochem. 234 8491.
  • 4
    Becker E., Soler R.M., Yuste V.J., Gine E., Sanz-Rodrigues C., Egea J., Martin-Zanca D., Comella J.X. (1998) Development of survival responsiveness to brain-derived neurotrophic factor, neurotrophin 3 and neurotrophin 4/5, but not to nerve growth factor, in cultured motoneurons from chick embryo spinal cord. J. Neurosci. 18 79037911.
  • 5
    Brandoli C., Sanna A., DeBernardi M.A., Follesa P., Brooker G., Mocchetti I. (1998) Brain-derived neurotrophic factor and basic fibroblast growth factor downregulate NMDA receptor function in cerebellar granule cells. J. Neurosci. 18 79537961.
  • 6
    Burgering B.M. & Coffer P.J. (1995) Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction. Nature 376 599602.
  • 7
    Calderó J., Ciutat D., Lladó J., Castán E., Oppenheim R.W., Esquerda J.E. (1997) Effects of excitatory amino acids on neuromuscular development in the chick embryo. J. Comp. Neurol. 387 7395.DOI: 10.1002/(SICI)1096-9861(19971013)387:1<73::AID-CNE7>3.0.CO;2-K
  • 8
    Calissano P., Ciotti M.T., Battistini L., Zona C., Angelini A., Merlo D., Mercanti D. (1993) Recombinant human insulin-like growth factor I exerts a trophic action and confers glutamate-resistant cerebellar granule cells. Proc. Natl. Acad. Sci. USA 90 87528756.
  • 9
    Camu W. & Henderson C.E. (1992) Purification of embryonic rat motoneurons by panning on a monoclonal antibody to the low-affinity NGF receptor. J. Neurosci. Methods 44 5970.
  • 10
    Carmignoto G., Pizzorusson T., Tia S., Vicini S. (1997) Brain-derived neurotrophic factor and nerve growth factor potentiate excitatory synaptic transmission in the rat visual cortex. J. Physiol. (Lond.) 498 153164.
  • 11
    Carter B.D. & Lewin G.R. (1997) Neurotrophins live and let die: does p75NTR decide? Neuron 18 187190.
  • 12
    Casaccia-Bonnefil P., Carter B.D., Dobrowsky R.T., Chao M.V. (1996) Death of oligodendrocytes mediated by the interaction of nerve growth factor with its receptor p75. Nature 383 716719.
  • 13
    Chao M.V. (1994) The p75 neurotrophin receptor. J. Neurobiol. 25 13731385.
  • 14
    Chao M.V. & Hempstead B.L. (1995) p75 and Trk: a two-receptor system. Trends Neurosci. 18 321326.
  • 15
    Choi D.W. (1988) Glutamate neurotoxicity and diseases of the nervous system. Neuron 1 623634.
  • 16
    Choi D.W. (1990) The role of glutamate neurotoxicity in hypoxicischemic neuronal death. Annu. Rev. Neurosci. 13 171182.
  • 17
    Curthoys N.P. & Watford M. (1993) Regulation of glutaminase activity and glutamine metabolism. Annu. Rev. Nutr. 15 133159.
  • 18
    D'Arcangelo G., Paradiso K., Shepherd D., Brehm P., Halegoua S., Mandel G. (1993) Neuronal growth factor regulation of two different sodium channel types through distinct signal transduction pathways. J. Cell Biol. 122 915921.
  • 19
    Davies A.M. (1994) The role of neurotrophins in the developing nervous system. J. Neurobiol. 25 13341348.
  • 20
    Denhardt D.T. (1996) Signal-transducing protein phosphorylation cascades mediated by Ras/Rho proteins in the mammalian cell: the potential for multiplex signalling. Biochem. J. 318 729747.
  • 21
    Dikic I., Batzer A.G., Blaikie P., Obermeier A., Ullrich A., Schlessinger J., Margolis B. (1995) Shc binding to nerve growth factor receptor is mediated by the phosphotyrosine interaction domain. J. Biol. Chem. 270 1512515129.
  • 22
    Dobrowsky R.T., Jenkins G.M., Hannun Y.A. (1995) Neurotrophins induce sphingomyelin hydrolysis: modulation by co-expression of p75NTR with Trk receptors. J. Biol. Chem. 270 2213522142.
  • 23
    Dudley D.T., Pang L., Decker S.J., Bridges A.J., Saltiel A.R. (1995) A synthetic inhibitor of the mitogen-activated protein kinase cascade. Proc. Natl. Acad. Sci. USA 92 76867689.
  • 24
    Erdö S.L., Michler A., Wolff J.R., Tytko H. (1990) Lack of excitotoxic cell death in serum-free cultures of rat cerebral cortex. Brain Res. 526 328332.
  • 25
    Escandon E., Soppet D., Rosenthal A., Mendoza-Ramirez J., Szönyi E., Burton L.E., Henderson C.E., Nikolics K. (1994) Regulation of neurotrophin receptor expression during embryonic and postnatal development. J. Neurosci. 14 20542068.
  • 26
    Fanger G.R., Jones J.R., Maue R.A. (1995) Differential regulation of neuronal sodium channel expression by endogenous and exogenous tyrosine kinase receptors expressed in rat pheochromocytoma cells. J. Neurosci. 15 202213.
  • 27
    Fawcett J.P., Bamji S.X., Causing C.G., Aloyz R., Ase A.R., Reader T.A., McLean, J.H., Miller F.D. (1998) Functional evidence that BDNF is an anterograde neuronal trophic factor in the CNS. J. Neurosci. 18 28082821.
  • 28
    Fernandez-Sanchez M.T. & Novelli A. (1993) Basic fibroblast growth factor protects cerebellar neurons in primary culture from NMDA and non-NMDA receptor mediated neurotoxicity. FEBS Lett. 335 124131.
  • 29
    Figurov A., Pozzo-Miller L.D., Olafsson P., Wang T., Lu B. (1996) Regulation of synaptic responses to high-frequency stimulation and LTP by neurotrophins in the hippocampus. Nature 381 706709.
  • 30
    Frade J.M., Rodríquez-Tébar A., Barde Y. (1996) Induction of cell death by endogenous nerve growth factor through its p75 receptor. Nature 383 166168.
  • 31
    Frandsen A. & Schousboe A. (1993) Excitatory amino acid-mediated cytotoxicity and calcium homeostasis in cultured neurons. J. Neurochem. 60 12021211.
  • 32
    Franke T.F., Yang S.I., Chan T.O., Datta K., Kazlauskas A., Morrison D.K., Kaplan D.R., Tsichlis P.N. (1995) The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase. Cell 81 727736.
  • 33
    Fryer H.J.L., Knox R.J., Strittmatter S.M., Kalb R.G. (1999) Excitotoxic death of a subset of embryonic motor neurons in vitro. J. Neurochem. 72 500513.
  • 34
    Hara K., Yonezawa K., Sakaue H., Ando A., Kotani K., Kitamura T., Kitamura Y., Ueda H., Stephans L., Jackson T.R., Hawkins P.T., Dhand R., Clark A.E., Holman G.D., Waterfield M.D., Kasuga M. (1994) 1-Phosphatidylinositol 3-kinase activity is required for insulin-stimulated glucose transport but not for RAS activation on CHO cells. Proc. Natl. Acad. Sci. USA 91 74157419.
  • 35
    Harman A.W. & Maxwell M.J. (1995) An evaluation of the role of calcium in cell injury. Annu. Rev. Pharmacol. Toxicol. 35 129144.
  • 36
    Harris A.J. & McCaig C.D. (1984) Motoneuron death and motor unit size during embryonic development of the rat. J. Neurosci. 4 1324.
  • 37
    Hartley D.M., Kurth M.C., Bjerkness L., Weiss J.H., Choi D.W. (1993) Glutamate receptor-induced 45Ca2+ accumulation in cortical cell culture correlates with subsequent neuronal degeneration. J. Neurosci. 13 19932000.
  • 38
    Hefti F. (1994) Neurotrophic factor therapy for nervous system degenerative disorders. J. Neurobiol. 25 14181435.
  • 39
    Henderson C.E., Camu W., Mettling C., Gouin A., Poulsen K., Karihaloo M., Rullamas J., Evans T., McMahon S.B., Armanini M.P., Berkemeier L., Philips H.S., Rosenthal A. (1993) Neurotrophins promote motor neuron survival and are present in embryonic limb bud. Nature 363 266270.
  • 40
    Henderson C.E., Bloch-Gallego E., Camu W. (1997) Purification and culture of embryonic motoneurons, in Neural Cell Culture: A Practical Approach (Cohen J. and Wilkin G., eds), pp. 6981. Oxford, London.
  • 41
    Hyrc K., Handran S.D., Rothman S.M., Goldberg M.P. (1997) Ionized intracellular calcium concentration predicts excitotoxic neuronal death: observations with low-affinity fluorescent calcium indicators. J. Neurosci. 17 66696677.
  • 42
    Ip N.Y., Stitt T.N., Tapley P., Klein R., Glass D.J., Fandl J., Greene L.A., Barbacid M., Yancopoulos G.D. (1993) Similarities and differences in the way neurotrophins interact with the Trk receptors in neuronal and nonneuronal cells. Neuron 10 137149.
  • 43
    Jacobson M. (1991) Neuroglial ontogeny, in Developmental Neurobiology, pp. 95139. Plenum, New York.
  • 44
    Kaplan D.R. & Stephens R.M. (1994) Neurotrophin signal transduction by the Trk receptor. J. Neurobiol. 25 14041417.
  • 45
    Klein R.D., Sherman D., Ho W., Stone D., Bennett G.L., Moffat B., Vandlen R., Simmons L., Gu Q., Hongo J., Devaux B., Poulsen K., Armanini M., Nozaki C., Asai N., Goddard A., Phillips H., Henderson C.E., Takahashi M., Rosenthal A. (1997) A GPI-linked protein that interacts with Ret to form a candidate neurturin receptor. Nature 387 717720.
  • 46
    Klocker N., Cellerino A., Bahr M. (1998) Free radical scavenging and inhibition of nitric oxide synthase potentiates the neurotrophic effects of brain-derived neurotrophic factor on axotomized retinal ganglion cells in vivo. J. Neurosci. 18 10381046.
  • 47
    Koh J., Gwang B.J., Lobner D., Choi D.W. (1995) Potentiated necrosis of cultured cortical neurons by neurotrophins. Science 268 573575.
  • 48
    Kohn J., Aloyz R.S., Toma J.G., Haak-Frendscho M., Miller F.D. (1999) Functionally antagonistic interactions between the TrkA and p75 neurotrophin receptors regulate sympathetic neuron growth and target innervation. J. Neurosci. 19 53935408.
  • 49
    Kotani K., Yonezawa K., Hara K., Ueda H., Kitamura Y., Sakaue H., Ando A., Chavanieu A., Calas B., Grigorescu F., Nishiyama M., Waterfield M.D., Kasuga M. (1994) Involvement of phosphoinositide 3-kinase in insulin- or IGF-1 mediated membrane ruffling. EMBO J. 13 23132321.
  • 50
    Lamballe F., Klein R., Barbacid M. (1991) trkC, a new member of the trk family of tyrosine protein kinases, is a receptor for neurotrophin-3. Cell 66 967979.
  • 51
    Lees G.J. (1993) Contributory mechanisms in the causation of neurodegenerative disorders. Neuroscience 54 287322.
  • 52
    Levine E.S., Dreyfus C.F., Black I.B., Plummer M.R. (1995a) Brain-derived neurotrophic factor rapidly enhances synaptic transmission in hippocampal neurons via postsynaptic tyrosine kinase receptors. Proc. Natl. Acad. Sci. USA 92 80748077.
  • 53
    Levine E.S., Dreyfus C.F., Black I.B., Plummer M.R. (1995b) Differential effects of NGF and BDNF on voltage-gated calcium currents in embryonic basa forebrain neurons. J. Neurosci. 15 30843091.
  • 54
    Levine E.S., Crozier R.A., Black I.B., Plummer M.R. (1998) Brain-derived neurotrophic factor modulates hippocampal synaptic transmission by increasing N-methyl-D-aspartic acid receptor activity. Proc. Natl. Acad. Sci. USA 18 1023510239.
  • 55
    Li Y., Zhang Y., Lester H.A., Shuman E.M., Davidson N. (1998) Enhancement of neurotransmitter release induced by brain-derived neurotrophic factor in cultured hippocampal neurons. J. Neurosci. 18 1023110240.
  • 56
    Lin S., Wu K., Levine E.S., Mount H.T., Suen P., Black I.B. (1998) BDNF acutely increases tyrosine phosphorylation of the NMDA receptor subunit 2B in cortical and hippocampal postsynaptic densities. Mol. Brain Res. 55 2027.
  • 57
    Lindholm D. (1994) Role of neurotrophins in preventing glutamate induced neuronal cell death. J. Neurol. 241 S16S18.
  • 58
    Lindsay R.M. (1994) Trophic protection of motor neurons: clinical potential in motor neuron diseases. J. Neurol. 241 S8S11.
  • 59
    Lipton S.A. & Rosenberg P.A. (1994) Excitatory amino acids as a final common pathway for neurologic disorders. N. Engl. J. Med. 330 613622.
  • 60
    Marshall C.J. (1995) Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation. Cell 80 179185.
  • 61
    Mattson M.P., Cheng B., Smith-Swintosky V.L. (1993) Mechanisms of neurotrophic factor protection against calcium- and free radical-mediated excitotoxic injury: implications for treating neurodegenerative disorders. Exp. Neurol. 124 8995.DOI: 10.1006/exnr.1993.1178
  • 62
    Mattson M.P., Lovell M.A., Furukawa K., Markesbery W.R. (1995) Neurotrophic factors attenuate glutamate-induced accumulation of peroxides, elevation of intracellular Ca2+ concentration, and neurotoxicity and increase antioxidant enzyme activities in hippocampal neurons. J. Neurochem. 65 17401751.
  • 63
    Metzger F., Wiese S., Sendtner M. (1998) Effect of glutamate on dendritic growth in embryonic rat motoneurons. J. Neurosci. 18 17351742.
  • 64
    Meyer-Franke A., Wilkinson G.A., Kruttgen A., Hu M., Munro E., Hanson M.G.J, Reichardt L.F., Barres B.A. (1998) Depolarization and cAMP elevation rapidly recruit TrkB to the plasma membrane of CNS neurons. Neuron 21 681693.
  • 65
    Morrison M.E. & Mason C.A. (1998) Granule neuron regulation of Purkinje cell development: striking a balance between neurotrophin and glutamate signaling. J. Neurosci. 18 35633573.
  • 66
    Neve R.L., Howe J.R., Hong S., Kalb R.G. (1997) Introduction of the glutamate receptor subunit 1 into motor neurons in vitro and in vivo using a recombinant herpes simplex virus. Neuroscience 79 435447.
  • 67
    Obermeier A., Bradshaw R.A., Seedorf K., Choidas A., Schlessinger J., Ullrich A. (1994) Neuronal differentiation signals are controlled by nerve growth factor receptor/Trk binding sites for SHC and PLC gamma. EMBO J. 13 15851590.
  • 68
    O'Donovan M.J., Ho S., Yee W. (1994) Calcium imaging of rhythmic network activity in the developing spinal cord of the chick embryo. J. Neurosci. 14 63546369.
  • 69
    Okada T., Kawano Y., Sakakibara T., Hazeki O., Ui M. (1994a) Essential role of phosphatidylinositol 3-kinase in insulin-induced glucose transport and antilipolysis in rat adipocytes. J. Biol. Chem. 269 35683573.
  • 70
    Okada T., Sakuma L., Fukui Y., Hazeki O., Ui M. (1994b) Blockage of chemotactic peptide-induced stimulation of neutrophils by wortmannin as a result of selective inhibition of phosphatidylinositol 3-kinase. J. Biol. Chem. 269 35633567.
  • 71
    Oppenheim R.W. (1989) The neurotrophic theory and naturally occurring motoneuron death. Trends Neurosci. 12 252255.
  • 72
    Patterson S.L., Abel T., Deuel T.A.S., Martin K.C., Rose J.C., Kandel E.R. (1996) Recombinant BDNF rescues deficits in basal synaptic transmission and hippocampal LTP in BDNF knockout mice. Neuron 16 11371145.
  • 73
    Pennica D., Arce V., Swanson T.A., Vejsada R., Pollock R.A., Armanini M., Dudley K., Phillips H.S., Rosenthal A., Kato A.C., Henderson C.E. (1996) Cardiotrophin-1, a cytokine present in embryonic muscle, supports long-term survival of spinal motoneurons. Neuron 17 6374.
  • 74
    Prehn J.H.M. (1996) Marked diversity in the action of growth factors on N-methyl-D-aspartate-induced neuronal degeneration. Eur. J. Pharmacol. 306 8188.
  • 75
    Rabizadeh S., Oh J., Zhong L., Yang J., Bitler C.M., Butcher L.L., Bredesen D.E. (1993) Induction of apoptosis by the low-affinity NGF receptor. Science 261 345348.
  • 76
    Randall R.J. & Thayer S.A. (1992) Glutamate-induced calcium transient triggers delayed calcium overload and neurotoxicity in rat hippocampal neurons. J. Neurosci. 12 18821895.
  • 77
    Ratan R.R., Murphy T.H., Baraban J.M. (1994) Macromolecular synthesis inhibitors prevent oxidative stress-induced apoptosis in embryonic cortical neurons by shunting cysteine from protein synthesis to glutathione. J. Neurosci. 14 43854392.
  • 78
    Roberg B., Torgner I.A., Kvanne E. (1995) The orientation of phosphate activated glutaminase in the inner mitochondrial membrane of synaptic and non-synaptic rat brain mitochondria. Neurochem. Int. 27 367376.
  • 79
    Roberson E.D., English J.D., Adams J.P., Selcher J.C., Kondratick C., Sweatt J.D. (1999) The mitogen-activated protein kinase cascade couples PKA and PKC to cAMP response element binding protein phosphorylation in area CA1 of hippocampus. J. Neurosci. 19 43374348.
  • 80
    Rodriguez-Viciana P., Warne P.H., Dhand R., Vanhaesebroeck B., Gout I., Fry M.J., Waterfield M.D., Downward J. (1994) Phosphatidylinositol-3-OH kinase as a direct target of Ras. Nature 370 527532.
  • 81
    Rudge J.S., Mather P.S., Pasnikowski E.M., Cai N., Corcoran T., Acheson A., Anderson K., Lindsay R.M., Weigand S.J. (1998) Endogenous BDNF protein increased in adult rat hippocampus after a kainic acid induced excitotoxic insult by exogenous BDNF is not neuroprotective. Exp. Neurol. 149 398410.
  • 82
    Samdani A.F., Newcamp C., Resink A., Facchinetti F., Hoffman B.E., Dawson V.L., Dawson T.M. (1997) Differential susceptibility to neurotoxicity mediated by neurotrophins and neuronal nitric oxide synthase. J. Neurosci. 17 46334641.
  • 83
    Shaw P.J. (1994) Excitotoxicity and motor neuron disease: a review of the evidence. J. Neurol. Sci. 124 (Suppl.) , 613.
  • 84
    Sholomenko G.N. & O'Donovan M.J. (1995) Development and characterization of pathways descending to the spinal cord in the embryonic chick. J. Neurophysiol. 73 12231233.
  • 85
    Solum D., Hughes D., Major M.S., Parks T.M. (1997) Prevention of normally occurring and deafferentiation-induced neuronal death in chick brainstem auditory neurons by periodic blockade of AMPA/kainate receptors. J. Neurosci. 17 47444751.
  • 86
    Sondell M., Lundborg G., Kanje M. (1999) Vascular endothelial growth factor has neurotrophic activity and stimulates axonal outgrowth, enhancing cell survival and Schwann cell proliferation in the peripheral nervous system. J. Neurosci. 19 57315740.
  • 87
    Soppet D., Escandon E., Maragos J., Middlemas D.S., Reid S.W., Blair J., Burton L.E., Stanton B.R., Kaplan D.R., Hunter T., Nikolics K., Parada L.F. (1991) The neurotrophic factors brain-derived neurotrophic factor and neurotrophin-3 are ligands for the trkB tyrosine kinase receptor. Cell 65 895903.
  • 88
    Takei N., Sasaoka K., Inoue K., Takahashi M., Endo Y., Hatanaka H. (1997) Brain-derived neurotrophic factor increases the stimulation-evoked release of glutamate and the levels of exocytosis-associated proteins in cultured cortical neurons from embryonic rats. J. Neurochem. 68 370375.
  • 89
    Tatter S.B., Galpern W.R., Isacson O. (1995) Neurotrophic factor protection against excitotoxic neuronal death. Neuroscientist 1 286297.
  • 90
    Traverse S., Gomez N., Paterson H., Marshall C.J., Cohen P. (1992) Sustained activation of the mitogen-activated protein (MAP) kinase cascade may be required for differentiation of PC12 cells. Comparison of the effects of nerve growth factor and epidermal growth factor. Biochem. J. 288 351355.
  • 91
    Treanor J.J.S., Goodman L., De Sauvage F., Stone D.M., Poulsen K.T., Beck C.D., Gray C., Armanini M.P., Pollack R.A., Hefti F., Phillips H.S., Goddard A., Moore M.W., Buj-Bello A., Davies A.M., Asai N., Takahashi M., Vandlen R., Henderson C.E., Rosenthal A. (1996) Characterization of a multicomponent receptor for GDNF. Nature 382 8083.
  • 92
    Trupp M., Arenas E., Fainzilber M., Nilsson A.S., Sieber B.A., Grigoriou M., Kilkenny C., Salazar-Grueso E., Pachnis V., Arumäe U., Sariola H., Saarma M., Ibáñez C.F. (1996) Functional receptor for GDNF encoded by the c-ret proto-oncogene. Nature 381 785789.
  • 93
    Vlahos C.J., Matter W.F., Hui K.Y., Brown R.F. (1994) A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002). J. Biol. Chem. 269 54215428.
  • 94
    Weskamp G. & Reichardt L.F. (1991) Evidence that biological activity of NGF is mediated through a novel subclass of high affinity receptors. Neuron 6 649663.
  • 95
    Wiese S., Metzger F., Holtmann B., Sendtner M. (1999) The role of p75NTR in modulating neurotrophin survival effects in developing motoneurons. Eur. J. Neurosci. 11 16681676.
  • 96
    Yamada M., Ohnishi H., Sano S., Nakatani A., Ikeuchi T., Hatanaka H. (1997) Insulin receptor substrate (IRS)-1 and IRS-2 are tyrosine-phosphorylated and associated with phosphatidylinositol 3-kinase in response to brain-derived neurotrophic factor in cultured cerebral cortical neurons. J. Biol. Chem. 272 3033430339.
  • 97
    Yan Q. & Johnson E.M. (1988) An immunohistochemical study of the nerve growth factor receptor in developing rats. J. Neurosci. 8 34813498.