SEARCH

SEARCH BY CITATION

References

  • Alves-Rodrigues A., Gregori L. & Figueiredo-Pereira M. E. (1998) Ubiquitin, cellular inclusions and their role in neurodegeneration. Trends Neurosci 21, 516520.DOI: 10.1016/s0166-2236(98)01276-4
  • Brown D. R., Schmidt B. & Kretzschmar H. A. (1996) Role of microglia and host prion protein in neurotoxicity of a prion protein fragment. Nature 380, 345347.
  • Brown D. R., Schulz-Schaeffer W. J., Schmidt B. & Kretzschmar H. A. (1997) Prion protein-deficient cells show altered response to oxidative stress due to decreased SOD-1 activity. Exp. Neurol. 146, 104112.DOI: 10.1006/exnr.1997.6505
  • Brown D. R., Wong B. S., Hafiz F., Clive C., Haswell S. & Jones I. M. (1999) Normal prion protein has an activity like that of superoxide dismutase. Biochem. J. 344, 15.DOI: 10.1042/0264-6021:3440001
  • Collinge J., Whittington M. A., Sidle K. C., Smith C. J., Palmer M. S., Clarke A. R. & Jefferys J. G. (1994) Prion protein is necessary for normal synaptic function. Nature 370, 295297.
  • Dobson C. M. (1999) Protein misfolding, evolution and disease. Trends Biochem. Sci. 24, 329332.DOI: 10.1016/s0968-0004(99)01445-0
  • Guan Z., Soderberg M., Sindelar P., Prusiner S. B., Kristensson K. & Dallner G. (1996) Lipid composition in scrapie-infected mouse brain: prion infection increases the levels of dolichyl phosphate and ubiquinone. J. Neurochem. 66, 277285.
  • Halliwell B. & Gutteridge J. M. C. (1999). Free radicals in biology and medicine. Oxford University Press, New York.
  • Ironside J. W., McCardle L., Hayward P. A. & Bell J. E. (1993) Ubiquitin immunocytochemistry in human spongiform encephalopathies. Neuropathol. Appl. Neurobiol. 19, 134140.
  • Keller J. N., Hanni K. B. & Markesbery W. R. (2000a) Impaired Proteasome Function in Alzheimer's Disease. J. Neurochem. 75, 436439.
  • Keller J. N., Huang F. F. & Markesbery W. R. (2000b) Decreased levels of proteasome activity and proteasome expression in aging spinal cord. Neuroscience 98, 149156.DOI: 10.1016/s0306-4522(00)00067-1
  • Lowe J., Blanchard A., Morrell K., Lennox G., Reynolds L., Billett M., Landon M. & Mayer R. J. (1988) Ubiquitin is a common factor in intermediate filament inclusion bodies of diverse type in man, including those of Parkinson's disease, Pick's disease, and Alzheimer's disease, as well as Rosenthal fibres in cerebellar astrocytomas, cytoplasmic bodies in muscle, and mallory bodies in alcoholic liver disease. J. Pathol. 155, 915.
  • Lowe J., McDermott H., Kenward N., Landon M., Mayer R. J., Bruce M., McBride P., Somerville R. A. & Hope J. (1990) Ubiquitin conjugate immunoreactivity in the brains of scrapie infected mice. J. Pathol. 162, 6166.
  • McGuire M. J., Croall D. E. & DeMartino G. N. (1988) ATP-stimulated proteolysis in soluble extracts of BHK 21/C13 cells. Evidence for multiple pathways and a role for an enzyme related to the high-molecular-weight protease, macropain. Arch. Biochem. Biophys. 262, 273285.
  • Manetto V., Perry G., Tabaton M., Mulvihill P., Fried V. A., Smith H. T., Gambetti P. & Autilio-Gambetti L. (1988) Ubiquitin is associated with abnormal cytoplasmic filaments characteristic of neurodegenerative diseases. Proc. Natl Acad. Sci. USA 85, 45014505.
  • Manson J. C., Clarke A. R., Hooper M. L., Aitchison L., McConnell I. & Hope J. (1994) 129/Ola mice carrying a null mutation in PrP that abolishes mRNA production are developmentally normal. Mol. Neurobiol. 8, 121127.
  • Okada K., Wangpoengtrakul C., Osawa T., Toyokuni S., Tanaka K. & Uchida K. (1999) 4-Hydroxy-2-nonenal-mediated impairment of intracellular proteolysis during oxidative stress. Identification of proteasomes as target molecules. J. Biol. Chem 274, 2378723793.
  • Perry G., Friedman R., Shaw G. & Chau V. (1987) Ubiquitin is detected in neurofibrillary tangles and senile plaque neurites of Alzheimer disease brains. Proc. Natl Acad. Sci. USA 84, 30333036.
  • Perry G., Raina A. K., Nunomura A., Wataya T., Sayre L. M. & Smith M. A. (2000) How important is oxidative damage? lessons from Alzheimer's disease. Free Radic Biol. Med. 28, 831834.DOI: 10.1016/s0891-5849(00)00158-1
  • Prusiner S. B. (1998) Prions. Proc. Natl Acad. Sci. USA 95, 1336313383.DOI: 10.1073/pnas.95.23.13363
  • Ramanathan M., Hassanain M., Levitt M., Seth A., Tolman J. S., Fried V. A. & Ingoglia N. A. (1999) Oxidative stress increases ubiquitin – protein conjugates in synaptosomes. Neuroreport 10, 37973802.
  • Sakaguchi S., Katamine S., Nishida N., Moriuchi R., Shigematsu K., Sugimoto T., Nakatani A., Kataoka Y., Houtani T., Shirabe S., Okada H., Hasegawa S., Miyamoto T. & Noda T. (1996) Loss of cerebellar Purkinje cells in aged mice homozygous for a disrupted PrP gene. Nature 380, 528531.
  • Sayre L. M., Perry G. & Smith M. A. (1999) Redox metals and neurodegenerative disease. Curr. Opin. Chem. Biol. 3, 220225.DOI: 10.1016/s1367-5931(99)80035-0
  • Smith M. A., Perry G., Richey P. L., Sayre L. M., Anderson V. E., Beal M. F. & Kowall N. (1996) Oxidative damage in Alzheimer's [letter]. Nature 382, 120121.
  • Tobler I., Gaus S. E., Deboer T., Achermann P., Fischer M., Rulicke T., Moser M., Oesch B., McBride P. A. & Manson J. C. (1996) Altered circadian activity rhythms and sleep in mice devoid of prion protein. Nature 380, 639642.
  • White A. R., Collins S. J., Maher F., Jobling M. F., Stewart L. R., Thyer J. M., Beyreuther K., Masters C. L. & Cappai R. (1999a) Prion protein-deficient neurons reveal lower glutathione reductase activity and increased susceptibility to hydrogen peroxide toxicity. Am. J. Pathol. 155, 17231730.
  • White A. R., Multhaup G., Maher F., Bellingham S., Camakaris J., Zheng H., Bush A. I., Beyreuther K., Masters C. L. & Cappai R. (1999b) The Alzheimer's disease amyloid precursor protein modulates copper- induced toxicity and oxidative stress in primary neuronal cultures. J. Neurosci. 19, 91709179.
  • Wong B. S., Pan T., Liu T., Li R. L., Gambetti P. & Sy M. S. (2000) Differential contribution of superoxide dismutase activity by prion protein in vivo. Biochem. Biophys. Res. Commun. 273, 136139.DOI: 10.1006/bbrc.2000.2911