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  • Ackerley S., Grierson A. J., Brownlees J., Thornhill P., Anderton B. H., Leigh P. N., Shaw C. E. and Miller C. C. (2000) Glutamate slows axonal transport of neurofilaments in transfected neurons. J. Cell Biol. 150, 165176.
  • Al-Chalabi A., Andersen P. M., Nilsson P., Chioza B., Andersson J. L., Russ C., Shaw C. E., Powell J. F. and Leigh P. N. (1999) Deletions of the heavy neurofilament subunit tail in amyotrophic lateral sclerosis. Hum. Mol. Genet. 8, 157164.
  • Bergeron C., Beric-Maskarel K., Muntasser S., Weyer L., Somerville M.J. and Percy M. E. (1994) Neurofilament light and polyadenylated mRNA levels are decreased in amyotrophic lateral sclerosis motor neurons. J. Neuropathol. Exp. Neurol. 53, 221230.
  • Brownlees J., Yates A., Bajaj N. P., Davis D., Anderton B. H., Leigh P.N., Shaw C. E. and Miller C. C. (2000) Phosphorylation of neurofilament heavy-chain side-arms by stress-activated proteinkinase-1b/Jun N-terminal kinase-3. J. Cell Sci. 113, 401407.
  • Bruijn L. I., Becher M. W., Lee M. K., Anderson K. L., Jenkins N. A., Copeland N. G., Sisodia S. S., Rothstein J. D., Borchelt D. R., Price D. L. and Cleveland D. W. (1997) ALS-linked SOD1 mutant G85R mediates damage to astrocytes and promotes rapidly progressive disease with SOD1-containing inclusions. Neuron 18, 327338.
  • Canete-Soler R. and Schlaepfer W. W. (2000) Similar poly (C)-sensitive RNA-binding complexes regulate the stability of the heavy and light neurofilament mRNAs. Brain Res. 867, 265279.
  • Canete-Soler R., Schwartz M. L., Hua Y. and Schlaepfer W. W. (1998a) Characterization of ribonucleoprotein complexes and their binding sites on the neurofilament light subunit mRNA. J. Biol. Chem. 273, 1265512661.
  • Canete-Soler R., Schwartz M. L., Hua Y. and Schlaepfer W. W. (1998b) Stability determinants are localized to the 3′-untranslated region and 3′-coding region of the neurofilament light subunit mRNA using a tetracycline-inducible promoter. J. Biol. Chem. 273, 1265012654.
  • Canete-Soler R., Silberg D. G., Gershon M. D. and Schlaepfer W. W. (1999) Mutation in neurofilament transgene implicates RNA processing in the pathogenesis of neurodegenerative disease. J. Neurosci. 19, 12731283.
  • Canete-Soler R., Wu J., Zhai J., Shamim M. and Schlaepfer W. W. (2001) p190RhoGEF binds to a destabilizing element in the 3′ untranslated region of light neurofilament subunit mRNA and alters the stability of the transcript. J. Biol. Chem. 276, 3204632050.
  • Carpenter S. (1968) Proximal axonal enlargement in motor neuron disease. Neurology 18, 841851.
  • Cashman N. R., Durham H. D., Blusztajn J. K., Oda K., Tabira T., Shaw I. T., Dahrouge S. and Antel J. P. (1992) Neuroblastoma x spinal cord (NSC) hybrid cell lines resemble developing motor neurons. Dev. Dyn. 194, 209221.
  • Cleveland D. W. (1999) From Charcot to SOD1: mechanisms of selective motor neuron death in ALS. Neuron 24, 515520.
  • Cookson M. R., Ince P. G. and Shaw P. J. (1998) Peroxynitrite and hydrogen peroxide induced cell death in the NSC34 neuroblastoma x spinal cord cell line: role of poly (ADP-ribose) polymerase. J.Neurochem. 70, 501508.
  • Dore S., Krieger C., Kar S. and Quirion R. (1996) Distribution and levels of insulin-like growth factor (IGF-I and IGF-II) and insulin receptor binding sites in the spinal cords of amyotrophic lateral sclerosis (ALS) patients. Brain Res. Mol. Brain Res. 41, 128133.
  • Duberley R. M., Johnson I. P., Anand P., Swash M., Martin J., Leigh P.N. and Zeman S. (1995) Ciliary neurotrophic factor receptor expression in spinal cord and motor cortex in amyotrophic lateral sclerosis. J. Neurol. Sci. 129, 109113.
  • Duberley R. M., Johnson I. P., Anand P., Leigh P. N. and Cairns N. J. (1997) Neurotrophin-3-like immunoreactivity and Trk C expression in human spinal motoneurones in amyotrophic lateral sclerosis. J. Neurol. Sci. 148, 3340.
  • Figlewicz D. A., Krizus A., Martinoli M. G., Meininger V., Dib M., Rouleau G. A. and Julien J. P. (1994) Variants of the heavy neurofilament subunit are associated with the development of amyotrophic lateral sclerosis. Hum. Mol. Genet. 3, 17571761.
  • Fray A. E., Dempster S., Williams R. E., Cookson M. R. and Shaw P. J. (2001) Glutamine synthetase activity and expression are not affected by the development of motor neuronopathy in the G93A SOD-1/ALS mouse. Brain Res. Mol. Brain Res. 94, 131136.
  • Gaspar E. M., Tokiwa M. A. and Doering L. C. (1997) Effects of neurotrophic factors and cell substrates on the differentiation of a sympathoadrenal progenitor cell line. J. Neurocytol. 26, 407422.
  • Gurney M. E., Pu H., Chiu A. Y., Dal Canto M. C., Polchow C. Y., Alexander D. D., Caliendo J., Hentati A., Kwon Y. H., Deng H. X. etal. (1994) Motor neuron degeneration in mice that express a human Cu, Zn superoxide dismutase mutation. Science 264, 17721775.
  • Hirano A., Nakano I., Kurland L. T., Mulder D. W., Holley P. W. and Saccomanno G. (1984) Fine structural study of neurofibrillary changes in a family with amyotrophic lateral sclerosis. J. Neuropathol. Exp. Neurol. 43, 471480.
  • Ince P. G., Tomkins J., Slade J. Y., Thatcher N. M. and Shaw P. J. (1998) Amyotrophic lateral sclerosis associated with genetic abnormalities in the gene encoding Cu/Zn superoxide dismutase: molecular pathology of five new cases, and comparison with previous reports and 73 sporadic cases of ALS. J. Neuropathol. Exp. Neurol. 57, 895904.
  • Itoh T., Sobue G., Ken E., Mitsuma T., Takahashi A. and Trojanowski J.Q. (1992) Phosphorylated high molecular weight neurofilament protein in the peripheral motor, sensory and sympathetic neuronal perikarya: system-dependent normal variations and changes in amyotrophic lateral sclerosis and multiple system atrophy. Acta Neuropathol. 83, 240245.
  • Julien J. P. and Beaulieu J. M. (2000) Cytoskeletal abnormalities in amyotrophic lateral sclerosis: beneficial or detrimental effects? J.Neurol. Sci. 180, 714.
  • Julien J. P., Meyer D., Flavell D., Hurst J. and Grosveld F. (1986) Cloning and developmental expression of the murine neurofilament gene family. Brain Res. 387, 243250.
  • Li B. S., Veeranna Gu J., Grant P. and Pant H. C. (1999) Activation of mitogen-activated protein kinases (Erk1 and Erk2) cascade results in phosphorylation of NF-M tail domains in transfected NIH 3T3 cells. Eur. J. Biochem. 262, 211217.
  • Lindenbaum M. H., Carbonetto S., Grosveld F., Flavell D. and Mushynski W. E. (1988) Transcriptional and post-transcriptional effects of nerve growth factor on expression of the three neurofilament subunits in PC-12 cells. J. Biol. Chem. 263, 56625667.
  • Menzies F., Cookson M. R., Chrzanowska-Lightowlers Z. M. A., Taylor R. W., Turnbull D. M., Dong L., Figlewicz D. A. and Shaw P. J. (2002) Mitochondrial dysfunction in a cell culture model of amyotrophic lateral sclerosis. Brain 125, 15221533.
  • Mutoh T., Sobue G., Hamano T., Kuriyama M., Hirayama M., Yamamoto M. and Mitsuma T. (2000) Decreased phosphorylation levels of TrkB neurotrophin receptor in the spinal cords from patients with amyotrophic lateral sclerosis. Neurochem. Res. 25, 239245.
  • Nguyen M. D., Lariviere R. C. and Julien J. P. (2001) Deregulation of Cdk5 in a mouse model of ALS: toxicity alleviated by perikaryal neurofilament inclusions. Neuron 30, 135147.
  • Nishio T., Sunohara N. and Furukawa S. (1998) Neutrophin switching in spinal motoneurons of amyotrophic lateral sclerosis. Neuroreport 9, 16611665.
  • Olsen M. K., Roberds S. L., Ellerbrock B. R., Fleck T. J., McKinley D.K. and Gurney M. E. (2001) Disease mechanisms revealed by transcription profiling in SOD1-G93A transgenic mouse spinal cord. Ann. Neurol. 50, 730740.DOI: 10.1002/ana.1252
  • Parhad I. M., Scott J. N., Cellars L. A., Bains J. S., Krekoski C. A. and Clark A. W. (1995) Axonal atrophy in aging is associated with a decline in neurofilament gene expression. J. Neurosci. Res. 41, 355366.
  • Peng I., Binder L. I. and Black M. M. (1986) Biochemical and immunological analyses of cytoskeletal domains of neurons. J. Cell Biol. 102, 252262.
  • Rosen D. R., Siddique T., Patterson D., Figlewicz D. A., Sapp P., Hentati A., Donaldson D., Goto J., O'Regan J. P., Deng H. X. et al. (1993) Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis. Nature 362, 5962.
  • Rouleau G. A., Clark A. W., Rooke K., Pramatarova A., Krizus A., Suchowersky O., Julien J. P. and Figlewicz D. (1996) SOD1 mutation is associated with accumulation of neurofilaments in amyotrophic lateral sclerosis. Ann. Neurol. 39, 128131.
  • Sawin K. E. and Mitchison T. J. (1995) Mutations in the kinesin-like protein Eg5 disrupting localization to the mitotic spindle. Proc. Natl Acad. Sci. USA 92, 42894293.
  • Schmidt M. L., Carden M. J., Lee V. M. and Trojanowski J. Q. (1987) Phosphate dependent and independent neurofilament epitopes in the axonal swellings of patients with motor neuron disease and controls. Lab. Invest. 56, 282294.
  • Schwartz M. L., Bruce J., Shneidman P. S. and Schlaepfer W. W. (1995) Deletion of 3′-untranslated region alters the level of mRNA expression of a neurofilament light subunit transgene. J. Biol. Chem. 270, 2636426369.
  • Strong M. J. (1999) Neurofilament metabolism in sporadic amyotrophic lateral sclerosis. J. Neurol. Sci. 169, 170177.
  • Tomkins J., Usher P., Slade J. Y., Ince P. G., Curtis A., Bushby K. and Shaw P. J. (1998) Novel insertion in the KSP region of the neurofilament heavy gene in amyotrophic lateral sclerosis (ALS). Neuroreport 9, 39673970.
  • Veeranna A. N. D., Ahn N. G., Jaffe H., Winters C. A., Grant P. and Pant H. C. (1998) Mitogen-activated protein kinases (Erk1,2) phosphorylate Lys-Ser-Pro (KSP) repeats in neurofilament proteins NF-H and NF-M. J. Neurosci. 18, 40084021.
  • Williamson T. L. and Cleveland D. W. (1999) Slowing of axonal transport is a very early event in the toxicity of ALS-linked SOD1 mutants to motor neurons. Nat. Neurosci. 2, 5056.
  • Williamson T. L., Bruijn L. I., Zhu Q., Anderson K. L., Anderson S. D., Julien J. P. and Cleveland D. W. (1998) Absence of neurofilaments reduces the selective vulnerability of motor neurons and slows disease caused by a familial amyotrophic lateral sclerosis-linked superoxide dismutase 1 mutant. Proc. Natl Acad. Sci. USA 95, 96319636.
  • Wong N. K., He B. P. and Strong M. J. (2000) Characterization of neuronal intermediate filament protein expression in cervical spinal motor neurons in sporadic amyotrophic lateral sclerosis (ALS). J.Neuropathol. Exp. Neurol. 59, 972982.
  • Wong P. C., Pardo C. A., Borchelt D. R., Lee M. K., Copeland N. G., Jenkins N. A., Sisodia S. S., Cleveland D. W. and Price D. L. (1995) An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria. Neuron 14, 11051116.