SEARCH

SEARCH BY CITATION

References

  • Bursztajn S., DeSouza R., McPhie D. L., Berman S. A., Shioi J., Robakis N. K. and Neve R. L. (1998) Overexpression in neurons of human presenilin-1 or a presenilin-1 familial Alzheimer disease mutant does not enhance apoptosis. J. Neurosci. 18, 97909799.
  • Busser J., Geldmacher D. S. and Herrup K. (1998) Ectopic cell cycle proteins predict the sites of neuronal cell death in Alzheimer's disease brain. J. Neurosci. 18, 28012807.
  • Chen Y., McPhie D. L., Hirschberg J. and Neve R. L. (2000) The amyloid precursor protein-binding protein APP-BP1 drives the cell cycle through the S-M checkpoint and causes apoptosis in neurons. J. Biol. Chem. 275, 89298935.
  • Chow N., Korenberg J. R., Chen X.-N. and Neve R. L. (1996) APP-BP1, a novel protein that binds to the carboxyl-terminal region of the amyloid precursor protein. J. Biol. Chem. 271, 1133911346 .
  • Chow N., Cox C., Callahan L. M., Weimer J. M., Guo L. and Coleman P. D. (1998) Expression profiles of multiple genes in single neurons of Alzheimer's disease. Proc. Natl Acad. Sci. USA 95, 96209625.
  • Coopersmith R. and Neve R. L. (1999) Expression of multiple proteins within single primary cortical neurons using a replication deficient HSV vector. BioTechniques 27, 11561159.
  • Cotman C. W. and Anderson A. J. (1995) A potential role for apoptosis in neurodegeneration and Alzheimer's disease. Mol. Neurobiol. 10, 1945.
  • Dealy M. J., Nguyen K. V. T., Lo J., Gstaiger M., Krek W., Elson D., Arbeit J. M., Kipreos E. T. and Johnson R. S. (1999) Loss of cul1 results in early embryonic lethality and dysregulation of cyclin E. Nat. Genet 23, 245248.
  • Deshaies R. J. (1999) SCF and Cullin/Ring H2-based ubiquitin ligases. Annu. Rev. Cell. Dev Biol. 15, 435467.
  • Ey P. L., Prowse S. J. and Jenkin C. R. (1978) Isolation of pure IgG1, IgG2a and IgG2b immunoglobulins from mouse serum using protein A-sepharose. Immunochem. 15, 429436.
  • Ghosh S., May M. J. and Kopp E. B. (1998) NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responses. Annu. Rev. Immunol. 16, 225260.
  • Gong L. and Yeh E. T. (1999) Identification of the activating and conjugating enzymes of the NEDD8 conjugation pathway. J. Biol. Chem. 274, 1203612042.
  • Grilli M., Ribola M., Alberici A., Valerio A., Memorandum M. and Spano P. (1995) Identification and characterization of a kappa B/Rel binding site in the regulatory region of the amyloid precursor protein gene. J. Biol. Chem. 270, 2677426777.
  • Guan K. L. and Dixon J. E. (1991) Eukaryotic proteins expressed in Escherichia coli: an improved thrombin cleavage and purification procedure of fusion proteins with glutathione S-transferase. Anal. Biochem. 192, 262267.
  • Guo W., Fu W., Xie J., Luo H., Sells S. F., Geddes J. W., Bondada V., Rangnekar . V. M. and Mattson M. P. (1998) Par-4 is a mediator of neuronal degeneration associated with the pathogenesis of Alzheimer disease. Nat. Med. 4, 957962.
  • Handeli S. and Weintraub H. (1992) The ts41 mutation in Chinese hamster cells leads to successive S phases in the absence of intervening G2, M, and G1. Cell 71, 599611.
  • Harlow E. and Lane D. (1988). Antibodies, a Laboratory Manual. Cold Spring Harbor, New York.
  • Hirschberg J. and Marcus M. (1982) Isolation by a replica-plating technique of. Chinese hamster temperature-sensitive cell cycle mutants. J. Cell. Phys. 13, 159166.
  • Hochstrasser M. (2000) Evolution and function of ubiquitin-like protein-conjugation systems. Nat. Cell Biol. 2, E153E157.
  • Hori T., Osaka F., Chiba T., Miyamoto C., Okabayashi K., Shimbara N., Kato S. and Tanaka K. (1999) Covalent modification of all members of human cullin family proteins by NEDD8. Oncogene 18, 68296834.
  • Iwabuchi K., P. L. Bartel B., Li R., Marraccino and S. Fields. (1994) Two cellular proteins that bind to wild-type but not mutant p53. Proc. Natl Acad. Sci. USA 91, 60986102.
  • Kaye K. M., Devergne O., Harada J. N., Izumi K. M., Yalamanchili R., Kieff E. and Mosialos G. (1996) Tumor necrosis factor receptor associated factor 2 is a mediator of NF-kappa B activation by latent infection membrane protein 1, the Epstein-Barr virus transforming protein. Proc. Natl Acad. Sci. USA 93, 1108511090.
  • Kipreos E. T., Lander L. E., Wing J. P., He W. W. and Hedgecock E. M. (1996) Cul-1 is required for cell cycle exit in C. elegans and identifies a novel gene family. Cell 85,. 829–839.
  • Lee E. Y., Chang C. Y., Hu N., Wang Y. C., Lai C. C., Herrup K., Lee W.  H. and Bradley A. (1992) Mice deficient for Rb are nonviable and show defects in neurogenesis and haematopoiesis. Nature 359, 288294.
  • Liu W.-K., Williams R., Hall F., Dickson D. and Yen S.-H. (1995) Detection of a. Cdc2-related kinase associated with Alzheimer paired helical filaments. Am. J. Pathol. 146, 228238.
  • Mattson M. P. and Camandola S. (2001) NF-kappaB in neuronal plasticity and neurodegenerative disorders. J. Clin. Invest. 107, 247254.
  • Mitchell T. and Sugden B. (1995) Stimulation of NF-kappa B-mediated transcription by mutant derivatives of the latent membrane protein of Epstein–Barr virus. J. Gen. Virol. 69, 29682976.
  • Naumovski L. and Cleary M. L. (1996) The p53-binding protein 53BP2 also interacts with Bc12 and impedes cell cycle progression at G2/M. Mol. Cell. Biol. 16, 38843892.
  • O'Neill L. A. J. and Kaltschmidt C. (1997) NF-kappa B: a crucial transcription factor for glial and neuronal cell function. TINS 20, 252258.
  • Ohh M., Kim W.Y., Moslehi J.J., Chen Y., Chau V., Read M.A. and Kaelin W.G. Jr (2002) An intact NEDD8 pathway is required for Cullin-dependent ubiquitylation in mammalian cells. EMBO Report 3, 177182.
  • Osaka F., Kawasaki H., Aida N., Saeki M., Chiba T., Kawashima S., Tanaka K. and Kato S. (1998) A new NEDD8-ligating system for cullin-4A. Genes Dev. 12, 22632268.
  • Perkins N. D. (2000) The Rel/NF-kappa B family: friend and foe. TIBS 25, 434440.
  • Pope W., Lambert M., Leypole B., Seupaul R., Sletten L., Krafft G. and Klein W. (1994) Microtubule-associated protein tau is hyperphosphorylated during mitosis in the human neuroblastoma cell line SH-SY5Y. Exp. Neurol. 126, 185194.
  • Del Pozo J. C. and Estelle M. (2000) F-box proteins and protein degradation: an emerging theme in cellular regulation. Plant Mol. Biol. 44, 123128.
  • Read M. A., Brownell J. E., Gladysheva T. B., Hottelet M., Parent L. A., Coggins M. B., Pierce J. W., Produst V. N., Luo R.-S., Chau V. and Palombella V. J. (2000) Nedd8 modification of cul-1 activates SCF (beta (TrCP)-dependent ubiquitination of. IkaapaBalpha. Mol. Cell Biol. 20, 23262333.
  • Ron D. and Dressler H. (1992) pGSTag – a versatile bacterial expression plasmid for enzymatic labeling of recombinant proteins. Biotechniques 13, 866869.
  • Samuels-Lev Y., O'Connor D. J., Bergamaschi D., Trigiante G., Hsieh J.-K., Zhong . S., Campargue I., Naumovski L., Crook T. and Lu X. (2001) ASPP proteins specifically stimulate the apoptotic function of p53. Mol. Cell 8, 781794.
  • Tamatani M., Che Y. H., Matsuzaki H., Ogawa S., Okado H., Miyake S., Mizuno T. and Tohyama M. (1999) Tumor necrosis factor induces Bcl-2 and Bcl-x expression through NFkappaB activation in primary hippocampal neurons. J. Biol. Chem. 274, 85318538.
  • Tateishi K., Omata M., Tanaka K. and Chiba T. (2001) The NEDD8 system is essential for cell cycle progression and morphogenetic pathway in mice. J. Cell Biol. 155, 571–579.
  • Vincent I., Rosado M. and Davies P. (1996) Mitotic mechanisms in Alzheimer's disease? J. Cell. Biol. 132, 413425.
  • Vincent I., Jicha G., Rosado M. and Dickson D. (1997) Aberrant expression of mitotic cdc2/cyclin B1 kinase in degenerating neurons of Alzheimer's disease brain. J. Neurosci. 17, 35883598.
  • Wang Y., Penfold S., Tang X., Hattori N., Riley P., Harper J. W., Cross J. C. and Tyers M. (1999) Deletion of the Cul1 gene in mice causes arrest in early embryogenesis and accumulation of cycline. Curr. Biol. 9, 11911194.
  • Yang J.-P., Hori M., Takahashi N., Kawabe T., Kato H. and Okamoto T. (1999) NF-kappaB subunit p65 binds to 53BP2 and inhibits cell death induced by 53BP2. Oncogene 18, 51775186.
  • Yang Y., Geldmacher D. S. and Herrup K. (2001) DNA replication precedes neuronal cell death in Alzheimer's disease. J. Neurosci. 21, 26612668.