The relationship between intraocular pressure and refractive error adjusting for age and central corneal thickness
Article first published online: 22 DEC 2003
Ophthalmic and Physiological Optics
Volume 24, Issue 1, pages 41–45, January 2004
How to Cite
Nomura, H., Ando, F., Niino, N., Shimokata, H. and Miyake, Y. (2004), The relationship between intraocular pressure and refractive error adjusting for age and central corneal thickness. Ophthalmic and Physiological Optics, 24: 41–45. doi: 10.1046/j.1475-1313.2003.00158.x
- Issue published online: 22 DEC 2003
- Article first published online: 22 DEC 2003
- Received: 12 May 2003 Revised form: 18 August 2003 Accepted: 20 September 2003
- central corneal thickness;
- epidemiological study;
- intraocular pressure;
- refractive error
Purpose: To investigate the relationship between intraocular pressure (IOP) and refractive errors after adjusting for age, central corneal thickness (CCT), and other related factors.
Methods: IOP, CCT and refractive errors were measured in the right eyes of 1855 subjects, aged 40–82 years, in a cross-sectional study design. Subjects were divided into groups by refractive status: hyperopia, emmetropia, mild myopia, moderate myopia, or high myopia. With adjustments for age, CCT, blood pressure, obesity, education, hypertension, diabetes, and smoking status, IOP was estimated for each refractive status using a general linear model.
Results: IOP increased with advancing degrees of myopia, even after adjustment for age, CCT, and other related factors (p = 0.011). Estimated IOP of moderate myopia was significantly higher than that of emmetropia (p = 0.022).
Conclusions: Our results confirm the positive association between IOP and increasing degrees of myopia. This finding would support the hypothesis that the relationship between glaucoma and myopia might be pressure mediated.