Proteomics in cancer research
Article first published online: 15 OCT 2002
International Journal of Gynecological Cancer
Volume 12, Issue 5, pages 409–423, September 2002
How to Cite
Wu, W., Hu, W. and Kavanagh, J. J. (2002), Proteomics in cancer research. International Journal of Gynecological Cancer, 12: 409–423. doi: 10.1046/j.1525-1438.2002.01200.x
- Issue published online: 15 OCT 2002
- Article first published online: 15 OCT 2002
- Accepted for publication June 27, 2002.
- clinical application;
Abstract. Wu W, Hu W, Kavanagh J. Proteomics in cancer research.
With the human genome sequence now determined, the field of molecular medicine is moving beyond genomics to proteomics. In the field of cancer research, the key question is: how can oncologists best use techniques of proteomics in basic research and clinical application? In the postgenomic era, proteomics promises the discovery of biomarkers and tumor markers for early detection and diagnosis, novel protein-based drug targets for anticancer therapy, and new endpoints for the assessment of therapeutic efficacy and toxicity. This review paper will explore key themes in proteomics and their application in clinical cancer research.