Alopecia Universalis in a Patient with Common Variable Immunodeficiency


Address correspondence to S. Sebnem Kiliç, M.D., Hacettepe University Faculty of Medicine, Ihsan Dogramaci Children's Hospital, Immunology Unit, Ankara, Turkey.


Abstract: A 12-year-old boy with common variable immunodeficiency (CVI) who developed severe alopecia is presented. His sister also had alopecia and recurrent infections and died of lung infection at the age of 7 years. The loss of hair in both children was total; the pathology of a scalp skin biopsy specimen was typical for alopecia areata. The boy was subjected to clinical and immunologic evaluation and the results were compatible with common variable immunodeficiency.