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Effect of Penicillin G on Corium Thickness in Linear Morphea of Childhood: An Analysis Using Ultrasound Technique


Address correspondence to Matthias Möhrenschlager, M.D., Department of Dermatology and Allergy Biederstein, Technical University of Munich, Biedersteiner Str. 29, D-80802 Munich, Germany.


Abstract: Linear morphea is the most common form of localized scleroderma in children. The pathogenesis of this disorder is unknown. We report a child with a 6-year history of linear morphea in whom intravenous administration of 5 MU aqueous penicillin G three times a day for 10 consecutive days caused reduction in the thickness of the corium as demonstrated by ultrasound measurements.

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