Evidence that AEC Syndrome and Bowen–Armstrong Syndrome Are Variable Expressions of the Same Disease
Article first published online: 4 JAN 2002
Volume 16, Issue 2, pages 103–107, March/April 1999
How to Cite
Zenteno, Venegas and Kofman-Alfaro (1999), Evidence that AEC Syndrome and Bowen–Armstrong Syndrome Are Variable Expressions of the Same Disease. Pediatric Dermatology, 16: 103–107. doi: 10.1046/j.1525-1470.1999.99009.x
- Issue published online: 4 JAN 2002
- Article first published online: 4 JAN 2002
Several clinical disorders combine ectodermal dysplasia (ED) and cleft lip and/or palate (CL/P). These conditions have been recognized as a group of diseases with a narrow phenotypic spectrum and multiple points of overlap. We report a patient with a clinical diagnosis of AEC syndrome (ankyloblepharon, ectodermal defects, and CL/P) who additionally has some features observed in a different ED-CL/P disorder, Bowen–Armstrong syndrome. Because of this clinical overlap, we suggest that AEC syndrome and Bowen–Armstrong syndrome may be variable manifestations of the same pathologic entity.