Lymphomatoid Granulomatosis in a 4-Year-Old Boy


Address correspondence to Ronald C. Hansen, M.D., 1501 N. Campbell, P.O. Box 245038, Tucson, AZ 85724.


Abstract: Lymphomatoid granulomatosis is a necrotizing angiocentric and angiodestructive infiltrative process involving primarily the lung, skin, central nervous system, and kidney. The incidence is highest in middle-aged men and is rare in children. We report a case of lymphomatoid granulomatosis involving both skin and lung in a 4-year-old boy. The disease progressed to peripheral T-cell lymphoma, which was unusual in light of recent evidence suggesting a B-cell origin in the majority of cases.