Antigliadin Antibodies Associated with Chronic Mucocutaneous Candidiasis
Article first published online: 21 OCT 2002
Volume 19, Issue 5, pages 415–418, September 2002
How to Cite
Garcia, Y. H., Díez, S. G., Aizpún, L. T. and Oliva, N. P. (2002), Antigliadin Antibodies Associated with Chronic Mucocutaneous Candidiasis. Pediatric Dermatology, 19: 415–418. doi: 10.1046/j.1525-1470.2002.00117.x
- Issue published online: 21 OCT 2002
- Article first published online: 21 OCT 2002
Abstract: Chronic mucocutaneous candidiasis (CMC) is a primary immunodeficiency disease clinically characterized by Candida infection of the skin, mucous membranes, or nails that is refractory to traditional treatment. We present a typical case of a 13-year-old boy with an onset of illness at 1 month of age in the form of oral thrush. At age 2–3 years the patient began to have external otitis caused by Candida albicans and recurrent upper respiratory tract infections. Analytical studies detected iron deficiency and circulating antigliadin antibodies. Immunologic findings excluded other possible immunodeficiencies. Significant clinical improvement was produced by therapy with orally administered fluconazole. The significance of antigliadin antibodies is discussed.