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Keywords:

  • blood pressure;
  • coronary heart disease;
  • risk factor;
  • pharmacist;
  • ambulatory care

OBJECTIVE:

To assess the effect of a physician and pharmacist teamwork approach to uncontrolled hypertension in a medical resident teaching clinic, for patients who failed to meet the recommended goals of the fifth Joint National Commission on Detection, Evaluation and Treatment of High Blood Pressure.

HYPOTHESIS:

Physician and pharmacist teamwork can improve the rate of meeting national blood pressure goals in patients with previously uncontrolled hypertension.

DESIGN:

A single-blinded randomized controlled trial lasting 6 months.

SETTING:

A primary care outpatient teaching clinic.

PATIENTS:

A sample of 95 adult hypertensive patients who failed to meet national blood pressure goals based on three consecutive visits over a 6-month period.

INTERVENTION:

Patients were randomly assigned to a control arm of standard medical care or to an intervention arm in which a physician and pharmacist worked together as a team.

MAIN RESULTS:

At study completion, the percentage of patients achieving national goals due to intervention was more than double the percentage in the control arm (55% vs 20%, p < .001). Systolic blood pressure declined 23 mm Hg in the intervention arm versus 11 mm Hg in the control arm ( p < .01). Diastolic blood pressure declined 14 and 3 mm Hg in the intervention and control arms, respectively ( p < .001). The intervention worked equally as well in men and women and demonstrated noticeable promise in a minority of mixed-ancestry Hawaiians in whom hypertension is of special concern.

CONCLUSIONS:

Patients who fail to achieve national blood pressure goals under standard outpatient medical care may benefit from a program that includes a physician and pharmacist teamwork approach.