Divalproex Sodium: Migraine Treatment and Monitoring
Version of Record online: 26 JUN 2002
Headache: The Journal of Head and Face Pain
Volume 36, Issue 4, pages 239–242, April 1996
How to Cite
Silberstein, S. D. and Wilmore, L. J. (1996), Divalproex Sodium: Migraine Treatment and Monitoring. Headache: The Journal of Head and Face Pain, 36: 239–242. doi: 10.1046/j.1526-4610.1996.3604239.x
- Issue online: 26 JUN 2002
- Version of Record online: 26 JUN 2002
- Accepted for publication November 10, 1995.
- Cited By
- divalproex sodium;
Divalproex sodium is an effective drug for the treatment of migraine. Most adverse drug events are transient and not of great clinical concern. Although rare, well-documented examples of liver toxicity have been reported in children under 2 years of age on polypharmacy. Additional cases occur in children under 10 who are receiving polypharmacy, particularly those who have intractable seizures and degenerative central nervous system disease. Clinicians who treat migraineurs with divalproex sodium do not need to be overly preoccupied with monitoring of drug levels and liver function tests. The most valuable test is clinical observation of the patient.