Clusterlike Headache as a First Sign of Brain Metastases of Lung Cancer


Dr. J. Tajti, Department of Neurology, Szent-Györgyi University Medical School, P.O. Box 397, H-6701 Szeged, Hungary.


We report on a patient with clusterlike headache and multiple brain metastases of lung cancer. Initially, cluster headache was suggested clinically by characteristic symptoms without any focal central nervous system signs. However, magnetic resonance imaging demonstrated multiple brain metastases. It is possible that tumor necrosis factor may have played a role in initiating the clusterlike headache.