Migraine With Aura: Segregation Analysis and Heritability Estimation
Article first published online: 26 JUN 2002
Headache: The Journal of Head and Face Pain
Volume 36, Issue 5, pages 320–322, May 1996
How to Cite
Kalfakis, N., Panas, M., Vassilopoulos, D. and Malliara-Loulakaki, S. (1996), Migraine With Aura: Segregation Analysis and Heritability Estimation. Headache: The Journal of Head and Face Pain, 36: 320–322. doi: 10.1046/j.1526-4610.1996.3605320.x
- Issue published online: 26 JUN 2002
- Article first published online: 26 JUN 2002
- Accepted for publication October 8, 1995.
- Cited By
- segregation analysis
A genetic study was performed in a group of 60 migraine patients and their first-degree relatives as well as in a group of sex- and age-matched controls. Segregation analysis showed that multifactorial inheritance seems to be the most probable mode of genetic transmission. Heritabilities were estimated according to the sex of probands and relatives.
Our findings favor multifactorial inheritance, but the contribution of a major gene can not be excluded.